CAS 154229-20-6

Pyridine, 3-androsta-3,5,16-trien-17-yl-

Description:

Pyridine, 3-androsta-3,5,16-trien-17-yl- (CAS 154229-20-6) is a chemical compound that features a pyridine ring fused with a steroid structure. This compound is characterized by its unique combination of a nitrogen-containing heterocyclic ring and a steroid backbone, which contributes to its potential biological activity. Pyridine itself is known for its aromatic properties and is often used as a solvent or in the synthesis of various organic compounds. The presence of the steroid moiety suggests that this compound may exhibit hormonal or bioactive properties, potentially influencing biological pathways. Its structural complexity may also impact its solubility, stability, and reactivity, making it of interest in medicinal chemistry and pharmacology. Additionally, the specific arrangement of functional groups and stereochemistry can significantly affect its interactions with biological targets, which is crucial for its application in drug development or as a biochemical probe. Overall, this compound represents a fascinating intersection of heterocyclic chemistry and steroid biochemistry.

Formula: C₂₄H₂₉N

InChI: InChI=1S/C24H29N/c1-23-13-4-3-7-18(23)8-9-19-21-11-10-20(17-6-5-15-25-16-17)24(21,2)14-12-22(19)23/h3,5-8,10,15-16,19,21-22H,4,9,11-14H2,1-2H3/t19-,21-,22-,23-,24+/m0/s1

InChI key: InChIKey=LAZGFPQCCUTDPH-NHFPKVKZSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)C(=CC3)C=CCC4)[H])[H])(CC=C2C=5C=CC=NC5)[H]

Synonyms:

• Pyridine, 3-androsta-3,5,16-trien-17-yl-
• Abiraterone Anhydro Impurity
• 3-((8R,9S,10R,13S,14S)-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15- decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
• 17-(Pyridin-3-yl)androsta-3,5,16-triene
• Abiraterone acetate impurity 1 (abiraterone)
• Abiraterone ImpurityABCDEFGHI
• Abiraterone Acetate IMP
• Anhydro Abiraterone/17-(Pyridin-3-yl)androsta-3,5,16-triene
• Anhydro Abiraterone
• 3-((8R,9S,10R,13S,14S)-10,13-dimethyl

Anhydro Abiraterone (3-((8R,9S,10R,13S,14S)-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(Pyridin-3-yl)androsta-3,5,16-triene)

CAS: 154229-20-6

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₂₄H₂₉N

Color and Shape: White Off-White Solid

Molecular weight: 331.23

Ref: 45-1A03430

Anhydro Abiraterone

CAS: 154229-20-6

Formula: C₂₄H₂₉N

Color and Shape: White To Off-White Solid

Molecular weight: 331.50

Ref: 4Z-A-8220

Anhydro Abiraterone

CAS: 154229-20-6

Formula: C₂₄H₂₉N

Molecular weight: 331.5

Ref: ST-EA-CP-A67035

Anhydro Abiraterone

CAS: 154229-20-6

Applications Anhydro Abiraterone is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

Formula: C₂₄H₂₉N

Color and Shape: Neat

Molecular weight: 331.49

Ref: TR-A637910

Anhydro abiraterone

Controlled Product

CAS: 154229-20-6

Anhydro abiraterone is a metabolite of abiraterone, which is a drug used in the treatment of prostate cancer. It has been shown to be active in the inhibition of human cytochrome P450 and has been found to be an impurity in commercial preparations of abiraterone. Anhydro abiraterone is almost insoluble in water, but can be purified by recrystallization from ethanol.

Formula: C₂₄H₂₉N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 331.49 g/mol

Ref: 3D-EGA22920