CAS 15423-89-9

Dexamethasone 17-propionate

Description:

Dexamethasone 17-propionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a derivative of dexamethasone, characterized by the addition of a propionate ester group at the 17-position of the steroid structure. This modification enhances its lipophilicity, allowing for improved absorption and prolonged action in the body. Dexamethasone 17-propionate is typically used in various therapeutic applications, including the treatment of inflammatory conditions, allergies, and certain autoimmune disorders. Its mechanism of action involves the modulation of gene expression, leading to reduced production of pro-inflammatory cytokines and other mediators. The compound is often administered via topical, intramuscular, or intravenous routes, depending on the clinical indication. As with other corticosteroids, potential side effects may include immunosuppression, metabolic changes, and effects on the endocrine system. Proper dosage and monitoring are essential to minimize adverse effects while maximizing therapeutic benefits.

Formula: C₂₅H₃₃FO₆

InChI: InChI=1S/C25H33FO6/c1-5-21(31)32-25(20(30)13-27)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,26)19(29)12-23(18,25)4/h8-9,11,14,17-19,27,29H,5-7,10,12-13H2,1-4H3/t14-,17+,18+,19+,22+,23+,24+,25+/m1/s1

InChI key: InChIKey=ITYMTTQVNYAJAA-OCUNRLNVSA-N

SMILES: O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](C[C@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Propanoate
• (11β,16α)-9-Fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
• Dexamethasone Propionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 17-propionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 17-propionate (8CI)
• Dexamethasone 17-propionate

Dexamethasone 17-Propionate

CAS: 15423-89-9

Formula: C₂₅H₃₃FO₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 448.5243

Ref: IN-DA00ADGU

Dexamethasone 17-Propionate

CAS: 15423-89-9

Formula: C₂₅H₃₃FO₆

Molecular weight: 448.53

Ref: 4Z-D-3647

Dexamethasone 17-Propionate-d5

Controlled Product

CAS: 15423-89-9

Formula: C₂₅D₅H₂₈FO₆

Color and Shape: Neat

Molecular weight: 453.56

Ref: TR-D298822

Dexamethasone 17-Propionate

Controlled Product

CAS: 15423-89-9

Applications A Dexamethasone Dipropionate metabolite.
References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),

Formula: C₂₅H₃₃FO₆

Color and Shape: Neat

Molecular weight: 448.52

Ref: TR-D298820

Dexamethasone 17-propionate

Controlled Product

CAS: 15423-89-9

Dexamethasone 17-propionate is a prodrug of dexamethasone that is converted to the active form in the liver. It is an adrenocortical steroid used for the treatment of inflammatory and allergic conditions, as well as many other disorders. Dexamethasone 17-propionate has been shown to be effective in reducing inflammation and suppressing immune responses, as well as decreasing erythrocyte sedimentation rates and plasma concentrations of C-reactive protein. The drug also has a long half-life which makes it useful for treating chronic conditions.

Formula: C₂₅H₃₃FO₆

Purity: Min. 95%

Molecular weight: 448.52 g/mol

Ref: 3D-FD21399

Dexamethasone 17-Propionate

CAS: 15423-89-9

Formula: C₂₅H₃₃FO₆

Molecular weight: 448.53

Ref: ST-EA-CP-D17016