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CAS 154444-97-0

:

casein kinase-I substrate

Description:
Casein kinase-I substrate, identified by the CAS number 154444-97-0, is a peptide or protein substrate that is specifically phosphorylated by casein kinase I enzymes. These enzymes are serine/threonine kinases that play a crucial role in various cellular processes, including cell cycle regulation, circadian rhythms, and signal transduction pathways. The substrate typically contains specific amino acid sequences that are recognized and modified by casein kinase I, leading to the addition of phosphate groups. This phosphorylation can alter the substrate's activity, stability, or interactions with other proteins, thereby influencing numerous biological functions. Casein kinase-I substrates are often studied in the context of their roles in cellular signaling and their implications in diseases, including cancer and neurodegenerative disorders. The characterization of such substrates involves understanding their structure, the specific phosphorylation sites, and the biological pathways they are involved in, making them significant in both basic research and potential therapeutic applications.
Formula:C85H139N27O35S
Synonyms:
  • H-Arg-Arg-Lys-Asp-Leu-His-Asp-Asp-Glu-Glu-Asp-Glu-Ala-Met-Ser-Ile-Thr-Ala-OH
  • Rrkdlhddeedeamsita
  • Casein Kinase I Substrate
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