CAS 154445-77-9

N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Description:

The chemical substance known as N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine, with the CAS number 154445-77-9, is a complex organic compound characterized by its intricate molecular structure. It features a sulfonamide group, which is known for its biological activity, particularly in pharmaceuticals. The presence of the benzofuran moiety contributes to its potential interactions with biological targets, while the fluorenylmethoxycarbonyl (Fmoc) group is commonly used in peptide synthesis as a protective group. The compound is likely to exhibit specific solubility characteristics, stability under certain conditions, and potential reactivity due to its functional groups. Its structure suggests potential applications in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. However, detailed studies would be necessary to fully elucidate its properties, including its pharmacokinetics, toxicity, and efficacy in biological systems.

Formula: C₃₄H₄₀N₄O₇S

InChI: InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1

InChI key: InChIKey=HNICLNKVURBTKV-NDEPHWFRSA-N

SMILES: C(OC(N[C@@H](CCCNC(NS(=O)(=O)C=1C(C)=C2C(=C(C)C1C)OC(C)(C)C2)=N)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Synonyms:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-5-[N′-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido]pentanoic acid
• (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]ornithine
• <span class="text-smallcaps">L</span>-Ornithine, N⁵-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-Arg(pbf)-OH
• FMOC-N-omega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
• Fmoc-<span class="text-smallcaps">L</span>-Arg(Pbf)
• Fmoc-L-Arg(Pbf)-OH
• N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-{N-[(2,2,4,5,7-pentamethyl-2,3-dihydro-1-benzofuran-6-yl)sulfonyl]carbamimidoyl}-D-ornithine
• N⁵-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-ornithine
• Na-Fmoc-Nw-Pbf-L-arginine
• L-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine

CAS: 154445-77-9

Formula: C₃₄H₄₀N₄O₇S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 648.78

Ref: 3B-F0729

Nα-Fmoc-N^w-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-arginine, 98%

CAS: 154445-77-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₄H₄₀N₄O₇S

Purity: 98%

Molecular weight: 648.78

Ref: 02-H59039

Fmoc-L-Arg(Pbf)-OH

CAS: 154445-77-9

M03398 - Fmoc-L-Arg(Pbf)-OH

Formula: C₃₄H₄₀N₄O₇S

Purity: 96 %

Color and Shape: Crystalline Powder

Molecular weight: 648.78

Ref: 10-M03398

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Pbf protection is especially recommended for multiple-Arg- and Trp-containinng peptides. TFA cleavage is best performed in the presence of a silane scavenger.

Formula: C₃₄H₄₀N₄O₇S

Purity: 99.4081%

Color and Shape: White

Molecular weight: 648.78

Ref: 01-4089151

FMOC-Arg(Pbf)-OH

CAS: 154445-77-9

Formula: C₃₄H₄₀N₄O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 648.7690

Ref: IN-DA0039MD

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH

Purity: 98%

Molecular weight: 648.77g/mol

Ref: 54-BI5913

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Formula: C₃₄H₄₀N₄O₇S

Purity: ≥ 99.0%

Color and Shape: White to almost white powder

Molecular weight: 648.77

Ref: 7W-GM9958

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH is an amido-resin that is used in the industrial preparation of polyamides and as a reactive component for the synthesis of various peptide or protein drugs. The polymerisation reaction leads to the formation of a linear chain with a high molecular weight and low viscosity. Fmoc-Arg(Pbf)-OH has been used as an envisaged component for the synthesis of acetylcholine, messenger RNA, and nicotinic acetylcholine receptor. Trifluoroacetic acid is commonly used as a solvent in this process.

Formula: C₃₄H₄₀N₄O₇S

Purity: Min. 98.0 Area-%

Molecular weight: 648.77 g/mol

Ref: 3D-FLR-1746-PI

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

The Fmoc-Arg(Pbf)-OH is a cyclic peptide that has been shown to have significant cytotoxicity against human tumor cells. It binds to integrin receptors, which are involved in transcriptional regulation and cellular proliferation. The Fmoc-Arg(Pbf)-OH has been shown to be hypoglycemic and it also possesses redox potential. The chemical biology of this compound is not yet known, but toxicity studies have shown that it is nontoxic in mice.

Formula: C₃₄H₄₀N₄O₇S

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 648.77 g/mol

Ref: 3D-FF15787

Fmoc-Arg(Pbf)-OH

Controlled Product

CAS: 154445-77-9

Applications Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Formula: C₃₄H₄₀N₄O₇S

Color and Shape: Neat

Molecular weight: 648.77

Ref: TR-F604100