CAS 154598-52-4: Efavirenz

Description:Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) primarily used in the treatment of HIV infection. It is characterized by its ability to inhibit the reverse transcriptase enzyme, which is crucial for the replication of the HIV virus. Chemically, efavirenz is a lipophilic compound, which contributes to its pharmacokinetic properties, including a long half-life and the ability to penetrate the central nervous system. The substance is typically administered orally and is often part of combination therapy to enhance efficacy and reduce the risk of resistance. Efavirenz is known for its side effects, which can include neuropsychiatric symptoms, rash, and potential effects on liver function. Its mechanism of action involves binding to the reverse transcriptase enzyme, leading to disruption of viral RNA conversion to DNA. The compound is classified under the World Health Organization's List of Essential Medicines, highlighting its importance in global health. As with any medication, monitoring for adverse effects and drug interactions is essential during treatment.

Formula:C₁₄H₉ClF₃NO₂

InChI:InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1

InChI key:InChIKey=XPOQHMRABVBWPR-ZDUSSCGKSA-N

SMILES:O=C1OC(C#CC2CC2)(C3=CC(Cl)=CC=C3N1)C(F)(F)F

Synonyms:
(4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
(S)-4-(2-Cyclopropylethynyl)-6-chloro-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
(S)-4-(Cyclopropylethynyl)-6-chloro-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
(S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(S)-Efavirenz
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-
See more synonyms
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (S)-
Dmp 266
Efavuirenz
L 743726
Stocrin
Sustiva

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Efavirenz REF: 3B-E0997CAS: 154598-52-4	>98.0%(HPLC)(N)	59.00 €	Thu 20 Mar 25
Efavirenz RS REF: 41-ICRS1411CAS: 154598-52-4	- - -	102.00 €	Tue 25 Mar 25
Efavirenz REF: 45-1234103CAS: 154598-52-4	- - -	1,044.00 €	Wed 26 Mar 25
(4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one REF: IN-DA0037PVCAS: 154598-52-4	98%	To inquire	Thu 27 Mar 25
Efavirenz REF: 4Z-E-0733CAS: 154598-52-4	- - -	To inquire	Fri 28 Mar 25
Efavirenz REF: 7W-GP6354CAS: 154598-52-4	≥ 98.0%	80.00 €~175.00 €	Fri 28 Mar 25
Efavirenz REF: 04-C13111100CAS: 154598-52-4	- - -	159.00 €	Tue 01 Apr 25
Efavirenz REF: 86-MM0919.00CAS: 154598-52-4	- - -	1,294.00 €	Tue 01 Apr 25
Efavirenz REF: TM-T2393CAS: 154598-52-4	99.2% - 99.83%	42.00 €~404.00 €	Thu 03 Apr 25
(S)-Efavirenz REF: TR-E425000CAS: 154598-52-4	- - -	126.00 €~422.00 €	Tue 08 Apr 25
Efavirenz - Bio-X ™ REF: 3D-BC164402CAS: 154598-52-4	Min. 95%	145.00 €	Mon 07 Apr 25
Efavirenz REF: 3D-FC30275CAS: 154598-52-4	Min. 95%	136.00 €~6,640.00 €	Mon 07 Apr 25
(S)-7,14-Dihydroxy Efavirenz REF: TR-D452974CAS: 154598-52-4	- - -	32,192.00 €	Wed 07 May 25
rac Efavirenz-8-d1 REF: TR-E425004CAS: 154598-52-4	- - -	14,422.00 €	Wed 07 May 25