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CAS 154630-93-0

:

2-(trifluoromethyl)piperidine

Description:
2-(Trifluoromethyl)piperidine is a chemical compound characterized by its piperidine ring, which is a six-membered saturated nitrogen-containing heterocycle. The presence of a trifluoromethyl group (-CF3) at the second position of the piperidine ring significantly influences its chemical properties, including its lipophilicity and reactivity. This compound is typically a colorless to pale yellow liquid or solid, depending on the temperature and purity. It exhibits a relatively high boiling point due to the strong electronegative influence of the trifluoromethyl group, which can also enhance its stability and resistance to oxidation. 2-(Trifluoromethyl)piperidine is often utilized in medicinal chemistry and the synthesis of pharmaceuticals, as the trifluoromethyl group can improve the biological activity and metabolic stability of drug candidates. Additionally, it may serve as an intermediate in the production of agrochemicals and other fluorinated compounds. Safety data should be consulted, as fluorinated compounds can pose specific health and environmental risks.
Formula:C6H10F3N
InChI:InChI=1/C6H10F3N/c7-6(8,9)5-3-1-2-4-10-5/h5,10H,1-4H2
SMILES:C1CCNC(C1)C(F)(F)F
Synonyms:
  • Piperidine, 2-(trifluoromethyl)-
  • 2-(Trifluoromethyl)piperidine
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