CAS 155-54-4

(±)-Dihydroorotic acid

Description:

(±)-Dihydroorotic acid, with the CAS number 155-54-4, is a bicyclic organic compound that plays a significant role in the biosynthesis of pyrimidines, which are essential components of nucleic acids. It is a white to off-white crystalline solid that is soluble in water and exhibits weak acidity due to the presence of carboxylic acid functional groups. The compound exists as a racemic mixture, meaning it contains equal amounts of both enantiomers, which can exhibit different biological activities. (±)-Dihydroorotic acid is an intermediate in the de novo synthesis pathway of uridine and cytidine nucleotides, making it crucial for cellular metabolism and proliferation. Its structural formula includes a pyrimidine ring and a carboxyl group, contributing to its reactivity and interactions in biochemical pathways. Additionally, it has been studied for its potential therapeutic applications, particularly in relation to cellular energy metabolism and certain metabolic disorders. Overall, (±)-Dihydroorotic acid is an important compound in both biochemistry and pharmacology.

Formula: C₅H₆N₂O₄

InChI: InChI=1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)

InChI key: InChIKey=UFIVEPVSAGBUSI-UHFFFAOYSA-N

SMILES: C(O)(=O)C1CC(=O)NC(=O)N1

Synonyms:

• 2,6-Dioxo-1,3-diazinane-4-carboxylic acid
• 2,6-Dioxohexahydropyrimidine-4-Carboxylic Acid
• 4,5-Dihydroorotic acid
• 4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-
• 5,6-Dihydroorotate
• 5,6-Dihydroorotic acid
• 5,6-Dihydrouracil-6-carboxylic acid
• 6-Hydrouracilcarboxylic acid
• <span class="text-smallcaps">DL</span>-4,5-Dihydroorotic acid
• <span class="text-smallcaps">DL</span>-Dihydroorotic acid
• Dihydro-<span class="text-smallcaps">DL</span>-orotic acid
• Dihydroorotic acid
• Hexahydro-2,6-dioxo-4-pyrimidinecarboxylic acid
• L-Dihydroorotate
• Hydroorotic acid

2,6-dioxo-1,3-diazinane-4-carboxylic acid

CAS: 155-54-4

Formula: C₅H₆N₂O₄

Molecular weight: 158.1121

Ref: IN-DA001NJM

Hydroorotic acid

CAS: 155-54-4

Hydroorotic acid（Dihydroorotic acid） is an endogenous metabolite，a potential biomarker for diabetic nephropathy and adrenal pheochromocytoma.

Formula: C₅H₆N₂O₄

Purity: 99.90%

Color and Shape: Solid

Molecular weight: 158.11

Ref: TM-T32116

DL-Dihydro-Orotic Acid

CAS: 155-54-4

Formula: C₅H₆N₂O₄

Molecular weight: 158.11

Ref: 4Z-O-031003

DL-Dihydoorotic Acid

Controlled Product

CAS: 155-54-4

Applications DL-Dihydoorotic Acid is used in the production of orotic acid and methyl dihydroorotate (D449975). DL-Dihydoorotic Acid is one of many components used for enhancing the biosynthesis of hyaluronic acid.

Formula: C₅H₆N₂O₄

Color and Shape: Neat

Molecular weight: 158.11

Ref: TR-D449970

2,6-Dioxohexahydropyrimidine-4-carboxylic acid

CAS: 155-54-4

Purity: 95+%

Molecular weight: 158.1130066

Ref: 10-F613922

2,6-Dioxo-1,3-diazinane-4-carboxylic acid

CAS: 155-54-4

2,6-Dioxo-1,3-diazinane-4-carboxylic acid is a natural compound that has been shown to have clinical relevance in the treatment of autoimmune diseases, such as type I diabetes. This compound is an inhibitor of xanthine oxidase and dihydroorotate dehydrogenase and has been shown to inhibit the activity of these enzymes in vitro. 2,6-Dioxo-1,3-diazinane-4-carboxylic acid may be administered to patients with type I diabetes to improve their energy metabolism and reduce oxidative stress levels. The pharmacokinetic properties of this molecule are still being investigated.

Formula: C₅H₆N₂O₄

Purity: Min. 95%

Molecular weight: 158.11 g/mol

Ref: 3D-AAA15554

DL-Dihydro-Orotic Acid

CAS: 155-54-4

Formula: C₅H₆N₂O₄

Molecular weight: 158.11

Ref: ST-EA-CP-O2004