CAS 155-97-5

Pyridostigmine

Description:

Pyridostigmine is a synthetic compound classified as a reversible inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the breakdown of the neurotransmitter acetylcholine. This inhibition leads to increased levels of acetylcholine at neuromuscular junctions, enhancing neuromuscular transmission and muscle contraction. Pyridostigmine is primarily used in the treatment of myasthenia gravis, a condition characterized by muscle weakness due to impaired communication between nerves and muscles. It is also utilized as a prophylactic treatment against nerve agent exposure in military settings. The substance is typically administered orally or intravenously and has a relatively short half-life, necessitating multiple doses throughout the day for sustained effect. Pyridostigmine is known for its favorable safety profile, although it can cause side effects such as gastrointestinal disturbances, increased salivation, and muscle cramps. Its chemical structure features a pyridine ring, which contributes to its pharmacological properties, and it is often formulated as bromide salt for improved stability and solubility.

Formula: C₉H₁₃N₂O₂

InChI: InChI=1S/C9H13N2O2/c1-10(2)9(12)13-8-5-4-6-11(3)7-8/h4-7H,1-3H3/q+1

InChI key: InChIKey=RVOLLAQWKVFTGE-UHFFFAOYSA-N

SMILES: O(C(N(C)C)=O)C1=C[N+](C)=CC=C1

Synonyms:

• 3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium
• 5-21-02-00078 (Beilstein Handbook Reference)
• Pyridostigminum
• BRN 1428269
• Pyridinium, 3-hydroxy-1-methyl-, dimethylcarbamate (ester)
• Pyridostigmine
• 3-(((Dimethylamino)carbonyl)oxy)-1-methylpyridinium
• Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-
• 3-[(dimethylcarbamoyl)oxy]-1-methylpyridinium
• Pyridinium, 3-(((dimethylamino)carbonyl)oxy)-1-methyl-
• UNII-19QM69HH21
• Pyridinium, 3-hydroxy-1-methyl-, dimethylcarbamate

Pyridostigmine Bromide

CAS: 101-26-8, 155-97-5

Formula: C₉H₁₃BrN₂O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 261.12

Ref: 3B-P1339

pyridostigmine

CAS: 155-97-5

pyridostigmine

Purity: ≥98%

Molecular weight: 181.21g/mol

Ref: 54-BUP07548

pyridostigmine

CAS: 155-97-5

Pyridostigmine(Regonol) is an acetylcholinesterase inhibitor that can treat myasthenia gravis by increasing acetylcholine at the postsynaptic motor endplate.

Formula: C₉H₁₃N₂O₂

Purity: 98.10%

Color and Shape: Solid

Molecular weight: 181.21

Ref: TM-T8631