CAS 15500-66-0
:Pancuronium bromide
Description:
Pancuronium bromide is a synthetic neuromuscular blocking agent primarily used in anesthesia to facilitate intubation and provide muscle relaxation during surgical procedures. It belongs to the class of non-depolarizing neuromuscular blockers and works by competitively inhibiting the action of acetylcholine at the neuromuscular junction, leading to muscle paralysis. The substance is characterized by its long duration of action compared to other neuromuscular blockers, making it particularly useful in certain surgical contexts. Pancuronium bromide is typically administered intravenously and is known for its minimal cardiovascular effects, although it can cause tachycardia in some patients. Its chemical structure includes a steroid backbone, which contributes to its pharmacological properties. The compound is soluble in water and has a relatively high molecular weight. Due to its potent effects, careful dosing and monitoring are essential to avoid complications such as prolonged paralysis or respiratory insufficiency. As with all neuromuscular blockers, pancuronium bromide should be used in a controlled medical environment with appropriate supportive measures in place.
Formula:C35H60Br2N2O4
InChI:InChI=1/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26?,27?,28?,29?,30-,31-,32-,33-,34-,35-;;/m0../s1
InChI key:InChIKey=NPIJXCQZLFKBMV-YTGGZNJNSA-L
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(C[C@H](OC(C)=O)[C@H](C4)[N+]5(C)CCCCC5)[H])(CC1)[H])[H])(C[C@@H]([C@@H]2OC(C)=O)[N+]6(C)CCCCC6)[H].[Br-]
Synonyms:- 1,1'-(3α,17β-Dihydroxy-5α-androstan-2β,16β-ylene)bis[1-methylpiperidinium] dibromide diacetate
- 1,1'-[(2Β,3Α,5Α,16Β,17Β)-3,17-Bis(Acetyloxy)Androstane-2,16-Diyl]Bis(1-Methyl)Piperidinium Dibromide
- 2β,16β-Dipiperidino-5α-androstane-3α,17β-diol diacetate dimethobromide
- 5α-Androstane-3α,17β-diol, 2β,16β-bis(1-methylpiperidinio)-, dibromide, diacetate
- Androstane, piperidinium deriv.
- Bromure De Pancuronium
- Bromurex
- Bromuro De Pancuronio
- Mioblock
- Na 97
- Nsc 293162
- Org NA 97
- Org-NE 35
- Pancuronium
- Pancuronium Bromide
- Pancuronium dibromide
- Pancuroniumbromid
- Pavulon
- Piperidinium, 1,1'-(3α,17β-dihydroxy-5α-androstan-2β,16β-ylene)bis[1-methyl-, dibromide, diacetate
- (2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2,16-bis(1-methylpiperidinium-1-yl)androstane dibromide
- (2beta,3alpha,8xi,9xi,14xi,16beta,17beta)-3,17-bis(acetyloxy)-2,16-bis(1-methylpiperidinium-1-yl)androstane dibromide
- Piperidinium, 1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)androstane-2,16-diyl]bis[1-methyl-, dibromide
- 2-beta,16-beta-bis(1-methylpiperidinio)androstane-3-alpha,17-beta-diol 3-alpha,17-beta-di(acetate) dibromide
- 3-alpha,17-beta-diacetoxy-2-beta,16-beta-dipiperidino-5-alpha-androstanedimeth
- 5alpha-androstan-3alpha,17beta-diol,2beta,16beta-dipipecolinio-,dibromide,di
- 1,1’-(3,17-bis(acetyloxy)androstane-2,16-diyl)bis(1-methylpiperidinium)dibro
- 1,1'-[(2b,3a,5a,16b,17b)-3,17-bis(acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide
- ethylpiperidinium]dibromide
- 3-alpha,17-beta-diacetoxy-2-beta,16-beta-dipiperidino-5-alpha-androstanedime
- 1,1’-[3alpha,17beta-bis(acetyloxy)-5alpha-androstane-2beta,16beta-diyl]bis[1-m
- 1,1'-(3A,17B-DIHYDROXY-2B,5A-ANDROSTAN-2B,16B-YLENE) BIS[1-METHYLPIPERIDINIUM] DIACETATE DIBROMIDE
- 1,1'-[(2BETA,3ALPHA,5ALPHA,16BETA,17BETA)-3,17-BIS(ACETYLOXY)ANDROSTANE-2,16-DIYL]BIS[1-METHYLPIPERIDINIUM]DIBROMIDE
- 3alpha,17beta-diacetoxy-2beta,16beta-dipiperidino-5alpha-androstanedimethobrom
- 5alpha-androstan-3alpha,17beta-diol,2beta,16beta-dipipecolinio-,dibromide,
- orgna97
- 16-diyl)bis(1-methyl-ostane-dibromide
- 2beta,16beta-dipiperidino-5alpha-androstane-3alpha,17beta-dioldiacetatedimetho
- diacetate
- 1,1’-(3alpha,17beta-dihydroxy-5alpha-androstan-2beta,16beta-ylene)bis[1-methyl
- See more synonyms
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Found 13 products.
Pancuronium Bromide
CAS:Formula:C35H60Br2N2O4Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:732.68Pancuronium bromide
CAS:Pancuronium bromideFormula:C35H60Br2N2O4Purity:92.2%Color and Shape:White SolidMolecular weight:730.29198PANCURONIUM BROMIDE CRS
CAS:PANCURONIUM BROMIDE CRSFormula:C35H60Br2N2O4Color and Shape:ModifiedMolecular weight:732.6699Pancuronium Bromide
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C35H60Br2N2O4Color and Shape:White Yellow Pink PowderMolecular weight:730.29198Pancuronium dibromide
CAS:Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.Formula:C35H60Br2N2O4Purity:99.86%Color and Shape:solidMolecular weight:732.67Pancuronium Bromide (Vecuronium Bromide EP Impurity B Dibromide)
CAS:Formula:C35H60N2O4·2BrMolecular weight:572.88 2*79.90Pancuronium bromide
CAS:Formula:C35H60Br2N2O4Purity:≥ 98.0%Color and Shape:White to pale pink powderMolecular weight:732.67Pancuronium Bromide
CAS:Controlled Product<p>Applications A potent steroidal neuromuscular blocking agent; muscle relaxant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Buckett, W.R. et al.: Br. J. Pharmacol. Chemother., 32, 671 (1968); Mol, W.E.M. et al.: Biochem. Pharmacol., 44, 1453 (1992); Playfor, S.D. et al.: Paediatric Clin. Pharmacol., 553 (2006);<br></p>Formula:C35H60N2O4·2BrColor and Shape:NeatMolecular weight:732.67Pancuronium bromide
CAS:Controlled Product<p>Steroidal neuromuscular blocking agent; antagonist of muscarinic receptors</p>Formula:C35H60Br2N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:732.67 g/mol
