CAS 155148-31-5

1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]

Description:

1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane], with CAS number 155148-31-5, is a complex organic compound characterized by its unique structure that incorporates a phenylene group linked by methylene bridges to a tetraazacyclotetradecane framework. This compound features multiple nitrogen atoms within its cyclic structure, which contributes to its potential chelating properties, allowing it to form stable complexes with metal ions. The presence of the phenylene moiety enhances its stability and may influence its solubility and reactivity. Typically, such compounds are of interest in coordination chemistry and materials science, particularly for applications in catalysis, drug delivery, or as ligands in metal-organic frameworks. The tetraazacyclotetradecane component suggests potential biological activity, making it a candidate for further investigation in medicinal chemistry. Overall, the compound's structural characteristics indicate a versatile nature, suitable for various applications in both academic research and industrial settings.

Formula: C₂₈H₅₄N₈

InChI: InChI=1/C28H54N8.8ClH.2H2O/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H;2*1H2

InChI key: InChIKey=UEUPDYPUTTUXLJ-UHFFFAOYSA-N

SMILES: C(C1=CC=C(CN2CCCNCCNCCCNCC2)C=C1)N3CCCNCCNCCCNCC3.Cl

Synonyms:

• 1,1'-(Benzene-1,4-Diyldimethanediyl)Bis-1,4,8,11-Tetraazacyclotetradecane Octahydrochloride Dihydrate
• 1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)
• 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)
• 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, octahydrochloride
• AMD 3100 octahydrochloride
• Amd 3100
• Jm 3100
• Plerixafore 8HCl
• Sid 791
• Bicyclam
• JM3100, SID791, 1,1μ-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride
• Plerixafor hcl
• amd3100 octahydrochloride hydrate
• Plerixafor 8HCl (AMD3100 8HCl)
• 1,1'-[1,4-PHENYLENEBIS(METHYLENE)]BIS-1,4,8,11-TETRAAZACYCLOTETRADECANE OCTAHYDROCHLORIDE
• Plerixafor 8HCl
• Plerixafor HCL(JM 3100)
• 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]
• JM3100
• AMD 3100 octahydrochloride, >=98%
• InSolution? CXCR4 Antagonist I, AMD3100
• Plerixafor (octahydrochloride)
• AMD 3100 octahydrochloride(8HCl)
• AMD3100 8HCl
• Plerixafor 8HCl (AMD3100)
• Plerixafor hydrochloride
• SID791 octahydrochloride
• AMD 3100 octahydroch
• Plerixafor hydrochloride salt
• Plerixafor Hydrochloride (1:8)
• Plerixafor 8HCl (AMD3100 8HCl) USP/EP/BP
• AMD3100 OCTAHYDROCHLORIDE
• Plerixafor(SynonyM: AMD3100 octahydrochloride hydrate)
• 1,4-Bis[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]benzene Octahydrochloride
• AMD3100 HCl
• AMD3100 OCTAHYDROCHLORIDE;AMD-3100; AMD 3100
• CS-907
• BISCYCLAM
• CXCR4 Antagonist I, AMD3100
• AMD3100 hydrate octahydrochloride
• Plerixafor-d8 8HCl
• 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride, min. 95 % (NMR)
• InSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem
• SID791
• AMD3100
• JM 3100 8HCl
• 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride hydrate
• JM3100 octahydrochloride
• Plerixafor 8HCl (DB06809)
• AMD3100 OCTAHYDROCHLORIDE HYDRATE ANHYDROUS
• CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem

AMD-3100 Octahydrochloride

CAS: 155148-31-5

Formula: C₂₈H₅₄N₈·8HCl

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 794.46

Ref: 3B-P2620

1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)

CAS: 155148-31-5

Formula: C₂₈H₆₂Cl₈N₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 794.4695

Ref: IN-DA001NNI

AMD3100 octahydrochloride hydrate

CAS: 155148-31-5

Formula: C₂₈H₅₄N₈·8HCl·xH₂O

Purity: ≥ 97.0% (anhydrous basis)

Color and Shape: White or off-white powder

Molecular weight: 794.47 (anhydrous)

Ref: 7W-GK7176

Plerixafor octahydrochloride

CAS: 155148-31-5

Plerixafor octahydrochloride

Purity: ≥95%

Molecular weight: 794.46g/mol

Ref: 54-BUP13171

Plerixafor-d8 8HCl

CAS: 155148-31-5

Formula: C₂₈H₄₆D₈N₈·8HCl

Color and Shape: White To Off-White Solid

Molecular weight: 510.84 8 36.46

Ref: 4Z-P-557

Plerixafor 8HCl

CAS: 155148-31-5

Formula: C₂₈H₅₄N₈·8HCl

Color and Shape: White To Off-White Solid

Molecular weight: 502.80 8 36.46

Ref: 4Z-P-551

1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene Octahydrochloride

CAS: 155148-31-5

1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene Octahydrochloride

Purity: 99%

Molecular weight: 794.47g/mol

Ref: 54-OR1009221

Plerixafor octahydrochloride

CAS: 155148-31-5

Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.

Formula: C₂₈H₆₂Cl₈N₈

Purity: 98.01% - 99.79%

Color and Shape: Solid

Molecular weight: 794.46

Ref: TM-T1776L

AMD 3100 octahydrochloride

CAS: 155148-31-5

Antagonises CXCR4 selectively by blocking Ca2+ release (IC50 from 0.02 to 0.13 µM). Studied in SDF-1/CFXCR4-dependent functions in HIV, rheumatoid arthritis and breast cancer metastasis. Enhances mobilization of hematopoietic stem cells (HSCs) and Hematopoietic progenitor cells (HPCs) for re-populating hematopoietic progenitors for transplants in vivo and attenuates cocaine-induced locomotor activation.

Formula: C₂₈H₆₂Cl₈N₈

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 794.47 g/mol

Ref: 3D-FA148913

Plerixafor octahydrochloride

CAS: 155148-31-5

Purity: 99%

Molecular weight: 794.46

Ref: 10-F979582

Plerixafor Hydrochloride (1:8)

Controlled Product

CAS: 155148-31-5

Stability Hygroscopic
Applications Plerixafor Hydrochloride (1:8), is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients. It is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).
References Xie, T., et al.: Science, 290, 328 (2000), Leone, D., et al.: J. Pharmacol. Exp. Ther., 305, 1150 (2003), Chigaev, A., et al.: J. Immunol. 178, 6828 (2007), Kiel, M., et al.: Cell Stem Cell, 1, 204 (2007),

Formula: C₂₈H₅₄N₈·8ClH

Color and Shape: Neat

Molecular weight: 794.47

Ref: TR-P580505