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CAS 155179-15-0

:

Zaragozic acid D2

Description:
Zaragozic acid D2, with the CAS number 155179-15-0, is a natural product derived from certain fungi, specifically from the genus *Penicillium*. It is known for its role as a potent inhibitor of squalene synthase, an enzyme involved in the biosynthesis of sterols, including cholesterol. This inhibition makes zaragozic acid D2 of interest in pharmaceutical research, particularly for its potential applications in treating hypercholesterolemia and other lipid-related disorders. The compound features a complex molecular structure characterized by multiple functional groups, including carboxylic acids and hydroxyl groups, which contribute to its biological activity. Additionally, zaragozic acid D2 exhibits antifungal properties, further highlighting its significance in medicinal chemistry. Its solubility and stability in various solvents can vary, influencing its bioavailability and efficacy in therapeutic applications. Overall, zaragozic acid D2 represents a valuable compound in the study of lipid metabolism and the development of cholesterol-lowering agents.
Formula:C36H50O14
InChI:InChI=1/C36H50O14/c1-4-5-6-7-8-9-13-21-27(38)48-29-28(39)34(49-30(31(40)41)35(46,32(42)43)36(29,50-34)33(44)45)22-15-20-26(47-24(3)37)23(2)16-14-19-25-17-11-10-12-18-25/h10-12,14,17-19,23,26,28-30,39,46H,4-9,13,15-16,20-22H2,1-3H3,(H,40,41)(H,42,43)(H,44,45)/b19-14+/t23?,26?,28-,29-,30-,34-,35-,36-/m1/s1
Synonyms:
  • (1R,3S,4S,5S,6R,7R)-1-[(7E)-4-(acetyloxy)-5-methyl-8-phenyloct-7-en-1-yl]-6-(decanoyloxy)-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid (non-preferred name)
  • Zaragozic acid D(2)
  • L-glycero-D-altro-Pentadec-14-en-7-ulo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13,14,15-hexptadeoxy-12-methyl-15-phenyl-, 11-acetate 5-decanoate, (7S,11xi,12xi,14E)-
  • L-glycero-D-altro-Pentadec-14-en-7-ulo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13,14,15-heptadeoxy-12-methyl-15-phenyl-, 11-acetate 5-decanoate, (7S,11ξ,12ξ,14E)- (9CI)
  • Zaragozic acid D2
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Found 1 products.
  • Zaragozic acid D(2)
    Targetmol
    + Info

    Zaragozic acid D(2)

    CAS:
    <p>Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>
    Formula:C36H50O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:706.77

    Ref: TM-T26348