CAS 155205-89-3

(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenamide

Description:

The chemical substance with the name "(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenamide" and CAS number "155205-89-3" is a complex organic compound characterized by its multi-ring structure and multiple functional groups. It features a heptenamide backbone, indicating the presence of an amide functional group and a conjugated double bond, which contributes to its reactivity and potential biological activity. The compound contains several hydroxyl (-OH) groups, which enhance its solubility in polar solvents and may influence its interactions with biological systems. The stereochemistry is significant, as indicated by the specific configurations at various chiral centers, which can affect the compound's pharmacological properties and its mechanism of action. This substance is of interest in medicinal chemistry and may exhibit potential therapeutic effects, although detailed studies would be necessary to elucidate its biological activity and applications.

Formula: C₂₃H₃₃NO₄

InChI: InChI=1S/C23H33NO4/c24-23(28)11-7-2-1-6-10-19-20(22(27)16-21(19)26)15-14-18(25)13-12-17-8-4-3-5-9-17/h1,3-6,8-9,14-15,18-22,25-27H,2,7,10-13,16H2,(H2,24,28)/b6-1-,15-14+/t18-,19+,20+,21-,22+/m0/s1

InChI key: InChIKey=RAGQWYIPCPFTJC-KDACTHKWSA-N

SMILES: C(/C=C\CCCC(N)=O)[C@@H]1[C@@H](/C=C/[C@H](CCC2=CC=CC=C2)O)[C@H](O)C[C@@H]1O

Synonyms:

• (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenamide
• 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-
• 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-, (5Z)-
• 5-Heptenamide, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-, [1R-[1α(Z),2β(1E,3S*),3α,5α]]-
• 9Alpha,11Alpha,15S-Trihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z,13E-Dien-1-Amide

Bimatoprost amide (0.10% wt/v in ETHANOL), min. 98%

CAS: 155205-89-3

Formula: C₂₃H₃₃NO₄

Purity: min. 98%

Color and Shape: Colorless to Yellowish Oil (SOLUTION IN 10% ETHANOL)

Molecular weight: 387.51

Ref: 08-06-6007

N-Desethyl Bimatoprost

CAS: 155205-89-3

N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide.

Formula: C₂₃H₃₃NO₄

Color and Shape: Solid

Molecular weight: 387.51

Ref: TM-T37939

Bimatoprost Impurity 3

CAS: 155205-89-3

Formula: C₂₃H₃₃NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 387.52

Ref: 4Z-B-2411

N-Desethyl Bimatoprost

CAS: 155205-89-3

Formula: C₂₃H₃₃NO₄

Molecular weight: 387.5

Ref: ST-EA-CP-B40013

N-Norbimatoprost

Controlled Product

CAS: 155205-89-3

Applications N-Norbimatoprost is a useful reagent for developing methods for treating epithelial-related conditions including hair loss.N-Norbimatoprost is also an analog of Bimatoprost (B386800), an synthetic prostamide and structurally related to prostaglandin F2α.
References Lipkin, P. and Lubit, B.: US 7514474 B2 20090407 (2009); Lipkin, P. and Lubit, B U.S. Pat. Appl. Publ. US 20110002866 A1 20110106 (2011); Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001); Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003); Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004)

Formula: C₂₃H₃₃NO₄

Color and Shape: Neat

Molecular weight: 387.51

Ref: TR-N661110