CAS 155206-00-1

Bimatoprost

Description:

Bimatoprost is a synthetic prostaglandin analog primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. The chemical structure of Bimatoprost features a long hydrocarbon chain with a carboxylic acid group, which contributes to its biological activity. It is typically administered as an eye drop solution and is known for its effectiveness in promoting eyelash growth, leading to its use in cosmetic applications as well. Bimatoprost has a relatively low molecular weight and is lipophilic, allowing it to penetrate biological membranes effectively. Its pharmacokinetics involve rapid absorption and metabolism, with a half-life that supports its therapeutic use. Side effects may include ocular hyperemia, eye irritation, and changes in eyelash pigmentation. Overall, Bimatoprost is a versatile compound with significant applications in both medical and cosmetic fields.

Formula: C₂₅H₃₇NO₄

InChI: InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1

InChI key: InChIKey=AQOKCDNYWBIDND-FTOWTWDKSA-N

SMILES: C(=C/[C@H](CCC1=CC=CC=C1)O)\[C@@H]2[C@@H](C/C=C\CCCC(NCC)=O)[C@@H](O)C[C@H]2O

Synonyms:

• (5E)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
• (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide
• (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
• (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
• 17-Phenyl-Tri-Norprostaglandin F2Α-Ethyl Amide
• 17-Phenyltrinor-PGF2α ethylamide
• 17-phenyl TRINOR prostaglandin F2ALPHA ethyl amide
• 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5Z)-
• 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-, (5Z)-
• 5-Heptenamide, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-N-ethyl-, [1R-[1α(Z),2β(1E,3S*),3α,5α]]-
• Agn 192024
• Bimatoprost(LUMIGAN)
• Bimatoprost(TM)
• Latisse
• Lumigan
• N-Ethyl-9Alpha,11Alpha,15S-Trihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z, 13E-Dien-1-Amide
• Prostamide

Bimatoprost

CAS: 155206-00-1

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Formula: C₂₅H₃₇NO₄

Color and Shape: White Off-White Powder

Molecular weight: 415.27226

Ref: 45-1071348

5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5Z)-

CAS: 155206-00-1

Formula: C₂₅H₃₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 415.5656

Ref: IN-DA001NQ8

Bimatoprost

CAS: 155206-00-1

Bimatoprost

Purity: ≥98%

Molecular weight: 415.57g/mol

Ref: 54-BUP09673

Bimatoprost, min. 98%

CAS: 155206-00-1

Formula: C₂₅H₃₇NO₄

Purity: min. 98%

Color and Shape: White to Off-white Powder

Molecular weight: 415.57

Ref: 08-06-6008

Bimatoprost

CAS: 155206-00-1

Bimatoprost

Purity: 99%

Molecular weight: 415.57g/mol

Ref: 54-OR1025538

Bimatoprost

CAS: 155206-00-1

Formula: C₂₅H₃₇NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 415.57

Ref: 4Z-B-241

Bimatoprost

CAS: 155206-00-1

Formula: C₂₅H₃₇NO₄

Purity: ≥ 97.0%

Color and Shape: White or off-white crystalline powder or crystals

Molecular weight: 415.57

Ref: 7W-GX7154

Bimatoprost-d5

CAS: 155206-00-1

Formula: C₂₅H₃₂D₅NO₄

Molecular weight: 420.60

Ref: 4Z-B-242

Bimatoprost

CAS: 155206-00-1

Formula: C₂₅H₃₇NO₄

Color and Shape: Neat

Molecular weight: 415.57

Ref: 86-MM3603.00

Bimatoprost Impurity 14

CAS: 155206-00-1

Formula: C₃₅H₅₃NO₆

Molecular weight: 583.81

Ref: 4Z-B-2422

Bimatoprost

CAS: 155206-00-1

Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular

Formula: C₂₅H₃₇NO₄

Purity: 98% - >99.99%

Color and Shape: Crystalline Solid

Molecular weight: 415.57

Ref: TM-T2538

Bimatoprost

CAS: 155206-00-1

Stability Light Sensitive
Applications Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Formula: C₂₅H₃₇NO₄

Color and Shape: White

Molecular weight: 415.57

Ref: TR-B386800

Bimatoprost-d5

Controlled Product

CAS: 155206-00-1

Applications Labelled Bimatoprost (B386800). Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Formula: C₂₅H₃₂D₅NO₄

Color and Shape: Neat

Molecular weight: 420.6

Ref: TR-B386802

Bimatoprost

CAS: 155206-00-1

A potent prostanoid receptor (FP) agonist and PGF2α analog. Its biological activity is mediated by action on prostamide receptors. Has therapeutic potential for glaucoma and ocular hypertension.

Formula: C₂₅H₃₇NO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 415.57 g/mol

Ref: 3D-FB18599

Bimatoprost

CAS: 155206-00-1

Formula: C₂₅H₃₇NO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 415.57

Ref: 3B-B6165

BIMATOPROST

CAS: 155206-00-1

Purity: 99%

Molecular weight: 415.5740051

Ref: 10-F794030

Bimatoprost Acid Ethyl Ester

Controlled Product

CAS: 155206-00-1

Applications Bimatoprost Acid Ethyl Ester is an impurity of Bimatoprost (B386800). Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),

Formula: C₂₅H₃₆O₅

Color and Shape: Neat

Molecular weight: 416.55

Ref: TR-B386875