(+)-3R,5S-Fluvastatin sodium salt is a synthetic compound belonging to the class of statins, which are primarily used to lower cholesterol levels in the blood. It functions as an HMG-CoA reductase inhibitor, effectively reducing the synthesis of cholesterol in the liver. This compound is characterized by its chiral centers, which contribute to its specific stereochemistry and biological activity. The sodium salt form enhances its solubility in aqueous solutions, making it suitable for pharmaceutical formulations. In terms of physical properties, fluvastatin sodium salt is typically a white to off-white powder, and it is stable under normal conditions but sensitive to light and moisture. Its pharmacokinetics involve absorption in the gastrointestinal tract, with a significant first-pass metabolism in the liver. The compound is primarily excreted in the bile, and its therapeutic effects include not only cholesterol reduction but also potential anti-inflammatory properties. As with all medications, it is important to consider potential side effects and contraindications when used in clinical settings.

(+)-3R,5S-FLUVASTATIN SODIUM SALT

155229-75-7: (+)-3R,5S-Fluvastatin sodium salt is a synthetic compound belonging to the class of statins, which are primarily used to lower cholesterol levels in the blood. It functions as an HMG-CoA reductase inhibitor, effectively reducing the synthesis of cholesterol in the liver. This compound is characterized by its chiral centers, which contribute to its specific stereochemistry and biological activity. The sodium salt form enhances its solubility in aqueous solutions, making it suitable for pharmaceutical formulations. In terms of physical properties, fluvastatin sodium salt is typically a white to off-white powder, and it is stable under normal conditions but sensitive to light and moisture. Its pharmacokinetics involve absorption in the gastrointestinal tract, with a significant first-pass metabolism in the liver. The compound is primarily excreted in the bile, and its therapeutic effects include not only cholesterol reduction but also potential anti-inflammatory properties. As with all medications, it is important to consider potential side effects and contraindications when used in clinical settings.

(3R,5S)-Fluvastatin, a synthetic HMG-CoA reductase inhibitor (IC50: 8 nM), activates Nrf2 for antioxidant defense.

CAS 155229-75-7

(+)-3R,5S-FLUVASTATIN SODIUM SALT

(3R,5S)-Fluvastatin

Ref: TM-T39036