CAS 155251-72-2

N-Boc-(R)​-2-​(3-​Thiazolidinylcarbony​l)​pyrrolidine

Controlled Product

CAS: 155251-72-2

Applications N-Boc-(R)​-2-​(3-​Thiazolidinylcarbony​l)​-1-​pyrrolidine, is an impurity of Teneligliptin (T018300), is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.
References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)

Formula: C₁₃H₂₂N₂O₃S

Color and Shape: Neat

Molecular weight: 286.39

Ref: TR-T344590

N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine

CAS: 155251-72-2

N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine is a molecule that is used to develop analytical methods. It is a key intermediate in the synthesis of metformin hydrochloride, an anti-diabetic drug. N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine can be used as a surrogate for impurities in pharmaceuticals and other substances. This product can be used to validate analytical methods and has been shown to have high sensitivity.
N-Boc-(R)-2-(3-thiazolidinylcarbonyl)pyrrolidine can be synthesized by reacting acetonitrile with melamine, which is an impurity found in products such as milk powder, baby formula, and wheat gluten. The compound is then purified using RP-HPLC.

Formula: C₁₃H₂₂N₂O₃S

Purity: Min. 95%

Molecular weight: 286.39 g/mol

Ref: 3D-FGA25172