CAS 1553-56-6

DEHYDROLITHOCHOLIC ACID

Description:

Dehydrolithocholic acid is a bile acid derivative characterized by its unique chemical structure, which includes a steroid nucleus with hydroxyl groups and a carboxylic acid functional group. It is a product of the metabolic conversion of lithocholic acid and is primarily found in the bile of various species. This compound exhibits amphipathic properties, allowing it to interact with both hydrophilic and hydrophobic environments, which is crucial for its role in emulsifying fats and aiding in their absorption in the digestive system. Dehydrolithocholic acid is also involved in the regulation of cholesterol metabolism and has been studied for its potential effects on lipid metabolism and gut health. Its CAS number, 1553-56-6, is used for identification in chemical databases. While it is not commonly used in clinical settings, understanding its biochemical roles can provide insights into digestive health and the metabolism of lipids. As with many bile acids, it may also have implications in various physiological and pathological processes, including liver function and metabolic disorders.

Formula: C₂₄H₃₈O₃

InChI: InChI=1/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-16,18-21H,4-14H2,1-3H3,(H,26,27)/t15-,16?,18+,19-,20+,21+,23+,24-/m1/s1

InChI key: InChIKey=KIQFUORWRVZTHT-OPTMKGCMSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(CC(=O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyms:

• (5-Beta)-Cholan-24-Oicaci
• (5Beta)-3-Oxocholan-24-Oic Acid
• (5Beta,17Alpha)-3-Oxocholan-24-Oic Acid
• (5β)-3-Oxocholan-24-oic acid
• 3-Keto-5Beta-Cholanic Acid
• 3-Ketocholanic Acid
• 3-Ketolithocholic acid
• 3-Ketolithocholicacid
• 3-Oxo-5-Beta-Cholan-24-Oicaci
• 3-Oxo-5-Beta-Cholan-24-Oicacid
• 3-Oxo-5β-cholan-24-oic acid
• 3-Oxo-5β-cholanic acid
• 3-Oxo-5β-cholanoic acid
• 3-Oxocholan-24-Oic Acid
• 3-Oxocholanic acid
• 3-Oxolithocholic acid
• 3-keto-5β-Cholan-24-oic acid
• 3-keto-5β-Cholanic acid
• 5Beta-Cholanic Acid-3-One
• 5β-Cholan-24-oic acid, 3-oxo-
• 5β-Cholanic acid, 3-oxo-
• 5β-Cholanic acid-3-one
• Cholan-24-oic acid, 3-oxo-, (5β)-
• Lithocholic acid, dehydro-
• Dehydrolithocholic acid
• 3-Oxo-5beta-cholanoic Acid
• 3-oxocholanicacid
• 3-oxo-5beta-cholanic acid
• 3-Keto-5β-cholanic acid, Dehydrolithocholic acid
• cell,factor,RAR-related orphan receptor,3 Oxo 5β cholanoic acid,TH17,RORγt,differentiation,acid,bile,Inhibitor,responses,transcription,inhibit,ROR,3Oxo5βcholanoic acid,immune,3-oxoLCA
• 3-oxolithocholicacid

3-Oxo-5β-cholanoic Acid

CAS: 1553-56-6

Formula: C₂₄H₃₈O₃

Purity: >95.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 374.57

Ref: 3B-O0500

Cholan-24-oic acid, 3-oxo-, (5β)-

CAS: 1553-56-6

Formula: C₂₄H₃₈O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 374.5567

Ref: IN-DA001NTC

3-Oxo-5Β-Cholanoic Acid

CAS: 1553-56-6

3-Oxo-5Β-Cholanoic Acid

Purity: 95%

Molecular weight: 374.56g/mol

Ref: 54-OR1024081

3-Oxo-5β-cholanoic acid

CAS: 1553-56-6

3-Oxo-5β-cholanoic acid

Purity: ≥98%

Molecular weight: 374.56g/mol

Ref: 54-BUP06851

Dehydrolithocholic Acid

CAS: 1553-56-6

Formula: C24H38O3

Purity: >95%

Color and Shape: Solid

Molecular weight: 374.56

Ref: 48-65-1100

3-Oxo-5β-cholanoic acid

CAS: 1553-56-6

Molecular weight: 374.565

Ref: 10-F986997

3-Oxo-5β-cholanoic Acid

Controlled Product

CAS: 1553-56-6

Applications 3-Oxo-5β-cholanoic Acid is a steroid compound with pharmacological activity. It is a bile acid. Also used in the preparation of lithocholic acid derivatives used as proteasome regulators.
References Iqbal, M. et al.: Steroids. 53, 413 (1989); Deyashiki, Y. et al.: Biochm. J., 282, 741 (1992);

Formula: C₂₄H₃₈O₃

Color and Shape: Neat

Molecular weight: 374.56

Ref: TR-O848490

3-Oxo-5beta-cholanoic acid

Controlled Product

CAS: 1553-56-6

3-Oxo-5β-cholanoic acid is a monoclonal antibody that inhibits the expression of target genes by binding to hydroxyl groups in the 3' untranslated region. The optimum pH for its activity is 7.2, but can be shifted to 5.0 or 8.0 depending on the assay conditions. It has been shown to inhibit the constitutive androstane receptor and 3β-hydroxysteroid dehydrogenase, which are enzymes involved in cholesterol biosynthesis. The rat liver microsomes and human liver cells are also inhibited by 3-oxo-5β-cholanoic acid, although this may not be due to its inhibition of these enzymes. This drug has shown no effect on wild-type mice, but has been shown to inhibit the growth of cancer cells in mice with a mutated gene for 3β-hydroxysteroid dehydrogenase.

Formula: C₂₄H₃₈O₃

Purity: Min. 95%

Molecular weight: 374.6 g/mol

Ref: 3D-FO178862

3-Oxo-5β-cholanoic acid

CAS: 1553-56-6

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directly

Formula: C₂₄H₃₈O₃

Purity: 98.01% - 99.86%

Color and Shape: Solid

Molecular weight: 374.56

Ref: TM-T13502