CAS 1553977-17-5

Ibrutinib-d5

CAS: 1553977-17-5

Formula: C₂₅H₁₉D₅N₆O₂

Color and Shape: White To Off-White Solid

Molecular weight: 445.54

Ref: 4Z-I-061001

Ibrutinib-d5

CAS: 1553977-17-5

Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.

Formula: C₂₅H₂₄N₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 445.53

Ref: TM-T11601

Ibrutinib d5

CAS: 1553977-17-5

Ibrutinib d5 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). BTK is a non-receptor protein tyrosine kinase that plays an important role in the B-cell receptor signaling pathway. Ibrutinib d5 binds to BTK, and blocks its ATP binding site, preventing it from phosphorylating other proteins. This inhibition reduces the phosphorylation of key downstream effectors, such as ZAP-70, which is involved in B-cell proliferation and activation. Ibrutinib d5 also inhibits activation of PI3K/Akt signaling pathways and suppresses cytokine production.

Formula: C₂₅H₂₄N₆O₂

Purity: Min. 95%

Molecular weight: 445.5 g/mol

Ref: 3D-DMC97717