CAS 155418-06-7

1-[2-[3-(3,4-Dichlorophenyl)-1-[2-(3-isopropoxyphenyl)acetyl]piperidin-3(S)-yl]ethyl]-4-phenyl-1-azoniabicyclo[2.2.2]octane benzenesulfonate

Description:

The chemical substance known as "1-[2-[3-(3,4-Dichlorophenyl)-1-[2-(3-isopropoxyphenyl)acetyl]piperidin-3(S)-yl]ethyl]-4-phenyl-1-azoniabicyclo[2.2.2]octane benzenesulfonate" with CAS number 155418-06-7 is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups and a bicyclic framework. This compound features a piperidine ring, which is a common motif in many pharmaceuticals, and is substituted with various aromatic groups, including a dichlorophenyl moiety and an isopropoxyphenyl group. The presence of the azabicyclo[2.2.2]octane structure contributes to its unique properties, potentially influencing its pharmacological activity. The sulfonate group enhances its solubility in polar solvents, which is crucial for biological activity and formulation. Overall, this compound may exhibit significant biological activity, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. However, specific biological properties and applications would require further investigation through empirical studies.

Formula: C₄₃H₅₀Cl₂N₂O₅S

InChI: InChI=1/C37H45Cl2N2O2.C6H6O3S/c1-28(2)43-32-11-6-8-29(24-32)25-35(42)40-19-7-14-37(27-40,31-12-13-33(38)34(39)26-31)18-23-41-20-15-36(16-21-41,17-22-41)30-9-4-3-5-10-30;7-10(8,9)6-4-2-1-3-5-6/h3-6,8-13,24,26,28H,7,14-23,25,27H2,1-2H3;1-5H,(H,7,8,9)/q+1;/p-1/t36?,37-,41?;/m1./s1

Synonyms:

• 1-{2-[(3S)-3-(3,4-dichlorophenyl)-1-{[3-(1-methylethoxy)phenyl]acetyl}piperidin-3-yl]ethyl}-4-phenyl-1-azoniabicyclo[2.2.2]octane benzenesulfonate
• SR-140333A(chloride)
• SR-140333B
• SR-140333(cation)
• Nolpitantium besilate

Nolpitantiumbesilate

CAS: 155418-06-7

Nolpitantiumbesilate (NB) is a drug that has been studied for its potential to treat hypertension. It has a number of effects on the cardiovascular system, including lowering blood pressure and inhibiting the release of PGE2 in rat models. NB also inhibits the activity of epidermal growth factor (EGF) and adenosine receptor antagonists. It also interacts with neurokinin-1 receptor, which is involved in inflammatory processes. NB also has an effect on sodium succinate, hydroxy group, and growth factor levels, as well as antimuscarinic properties. It may be used to treat chronic bronchitis due to its ability to inhibit the proliferation of cells that line the airways.

Purity: Min. 95%

Ref: 3D-FN176225

Nolpitantium besilate

CAS: 155418-06-7

Nolpitantium besilate is a neurokinin-1 receptor antagonist.

Formula: C₄₃H₅₀Cl₂N₂O₅S

Color and Shape: Solid

Molecular weight: 777.84

Ref: TM-T70455