CAS 155428-00-5

alniditan

Description:

Alniditan is a chemical compound primarily recognized for its application in the treatment of migraine headaches. It belongs to the class of drugs known as selective serotonin receptor agonists, specifically targeting the 5-HT_1B and 5-HT_1D subtypes. This mechanism of action helps to alleviate migraine symptoms by inducing vasoconstriction of cranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides. Alniditan is typically administered in a form suitable for acute migraine relief, and its pharmacokinetics suggest a relatively rapid onset of action. The compound is characterized by its specific molecular structure, which contributes to its efficacy and safety profile. As with many medications, potential side effects may include dizziness, fatigue, or gastrointestinal disturbances, and it is essential for users to consult healthcare professionals for appropriate usage guidelines. Overall, alniditan represents a targeted approach in migraine management, reflecting advancements in pharmacological therapies for this condition.

Formula: C₁₇H₂₈Cl₂N₄O

InChI: InChI=1/C17H26N4O.2ClH/c1-2-6-16-14(5-1)7-8-15(22-16)13-18-9-3-10-19-17-20-11-4-12-21-17;;/h1-2,5-6,15,18H,3-4,7-13H2,(H2,19,20,21);2*1H/t15-;;/m1../s1

Synonyms:

• N-[(2R)-3,4-dihydro-2H-chromen-2-ylmethyl]-N'-(1,4,5,6-tetrahydropyrimidin-2-yl)propane-1,3-diamine dihydrochloride
• Alniditan HCl
• Alniditan dihydrochloride [USAN]
• (R)-N-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-N'-(1,4,5,6-tetrahydro-2-pyrimidinyl)-1,3-propanediamine dihydrochloride
• N-[(2R)-3,4-dihydro-2H-chromen-2-ylmethyl]-N'-(1,4,5,6-tetrahydropyrimidin-2-yl)propane-1,3-diamine
• 1,3-Propanediamine, N-((3,4-dihydro-2H-1-benzopyran-2-yl)methyl)-N'-(1,4,5,6-tetrahydro-2-pyrimidinyl)-,dihydrochloride, (R)-
• N-(3,4-Dihydro-2H-1-benzopyran-2-yl methyl)-N'-(1,4,5,6-tetrahydro-2-pyrimidinyl)-1,3-propanediamine dihydrochloride
• (-)-2-((3-(((R)-2-Chromanylmethyl)amino)propyl)amino)-1,4,5,6-tetrahydropyrimidine dihydrochloride
• Alniditan dihydrochloride

Alniditan dihydrochloride

CAS: 155428-00-5

Alniditan dihydrochloride is a drug that belongs to the class of 5-HT1A receptor agonists. It has been shown to have significant effects on carotid artery blood flow in vivo and has been found to be an effective treatment for patients with carotid artery stenosis. Alniditan dihydrochloride also has significant effects on hippocampal formation, which may be due to its ability to inhibit the production of messenger RNA and protein synthesis.

Formula: C₁₇H₂₈Cl₂N₄O

Purity: Min. 95%

Molecular weight: 375.3 g/mol

Ref: 3D-FGA42800

Alniditan dihydrochloride

CAS: 155428-00-5

Alniditan dihydrochloride is a potent 5-HT1D agonist and migraine-abortive agent.

Formula: C₁₇H₂₈Cl₂N₄O

Color and Shape: Solid

Molecular weight: 375.34

Ref: TM-T26598