CAS 155471-08-2

JWH-015

Description:

JWH-015 is a synthetic cannabinoid that belongs to a class of compounds known as indole derivatives. It was developed by Dr. John W. Huffman and is known for its high affinity for cannabinoid receptors, particularly CB1 and CB2, which are part of the endocannabinoid system in the human body. This compound is often studied for its potential therapeutic effects, including analgesic and anti-inflammatory properties. JWH-015 is typically encountered in research contexts and is not approved for medical use. It is important to note that synthetic cannabinoids can exhibit unpredictable effects and may pose significant health risks, including psychological and physiological side effects. The substance is often associated with recreational use and has been included in various drug legislation due to its potential for abuse. As with many synthetic cannabinoids, the legal status of JWH-015 varies by jurisdiction, and its use is often subject to regulation.

Formula: C₂₃H₂₁NO

InChI: InChI=1/C23H21NO/c1-3-15-24-16(2)22(20-12-6-7-14-21(20)24)23(25)19-13-8-10-17-9-4-5-11-18(17)19/h4-14H,3,15H2,1-2H3

InChI key: InChIKey=LJSBBBWQTLXQEN-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(N(CCC)C1C)=CC=CC2)C=3C4=C(C=CC3)C=CC=C4

Synonyms:

• (2-Methyl-1-Propyl-1H-Indol-3-Yl)-1-Naphthalenylmethanone
• (2-methyl-1-propyl-1H-indol-3-yl)(naphthalen-1-yl)methanone
• Methanone, (2-methyl-1-propyl-1H-indol-3-yl)-1-naphthalenyl-
• JWH 015
• JWH-015 (1.0mg/ml in Acetonitrile)
• Zinc02577049
• (2-methyl-1-propylindol-3-yl)-naphthalen-1-ylmethanone

JWH-015 ((2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone) 1.0 mg/ml in Acetonitrile

Controlled Product

CAS: 155471-08-2

Color and Shape: Single Solution

Ref: 61-AMP1275.72-11

JWH-015 ((2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone) 0.1 mg/ml in Acetonitrile

Controlled Product

CAS: 155471-08-2

Color and Shape: Single Solution

Ref: 61-AMP1275.72-12

JWH-015

CAS: 155471-08-2

Formula: C₂₃H₂₁NO

Molecular weight: 327.42

Ref: 7W-GK5474

JWH-015 ((2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone)

Controlled Product

CAS: 155471-08-2

Color and Shape: Neat

Ref: 61-FOR1275.72

JWH-015

Controlled Product

CAS: 155471-08-2

Applications A cannabimimetic indole derivative that acts as a CB2 receptor agonist with weak CB2 activity. It has been shown to possess immunomodulatory effects and may be useful in the treatment of pain and inflammation. Synthetic cannabinoids
References Aung, M.M. et al.: Drug Alc. Depend., 60, 133 (2000); Ghosh, S. et al.: Mol. Immunol., 43, 2169 (2006); Ehrhart, J. et al.: J. Neuroinflam., 2, 29 (2005); Romero-Sandoval, A. et al.: Anethesiol., 106, 787 (2007);

Formula: C₂₃H₂₁NO

Color and Shape: Neat

Molecular weight: 327.42

Ref: TR-J211350

JWH-015 (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 155471-08-2

Formula: C₂₃H₂₁NO

Color and Shape: Single Solution

Molecular weight: 327.42

Ref: TR-KIT5430

JWH 015

Controlled Product

CAS: 155471-08-2

JWH 015 is a cannabinoid that binds to the CB2 receptor and activates it, which induces apoptosis in cancer cells. JWH 015 has been shown to be effective against bone cancer, but not against colon cancer. It has also been shown to inhibit the growth of colon cancer cells in vitro by inhibiting the proliferation of cells and inducing apoptosis. JWH 015 may have potential as a chemotherapeutic agent for treating colorectal cancers. It does not bind to the CB1 receptors found on neurons and so does not cause any psychoactive effects.

Formula: C₂₃H₂₁NO

Purity: Min. 95%

Molecular weight: 327.42 g/mol

Ref: 3D-FJ24749