CAS 15569-85-4

rac Cotinine

Description:

Rac Cotinine, with the CAS number 15569-85-4, is a chemical compound that serves as a metabolite of nicotine, the primary alkaloid found in tobacco. It is a pyridine derivative and exhibits a chiral structure, existing as a racemic mixture of its enantiomers. Rac Cotinine is primarily recognized for its role in pharmacology and toxicology, particularly in studies related to smoking cessation and nicotine dependence. The compound is known for its relatively long half-life compared to nicotine, making it a useful biomarker for tobacco exposure. In terms of solubility, rac Cotinine is generally soluble in water and organic solvents, which facilitates its detection in biological samples. Its pharmacological effects include mild stimulant properties, although it is less potent than nicotine itself. Additionally, rac Cotinine has been investigated for potential therapeutic applications, including neuroprotective effects and cognitive enhancement. Overall, its significance in both research and clinical settings underscores its importance in understanding nicotine's impact on health.

Formula: C₁₀H₁₂N₂O

InChI: InChI=1/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3

SMILES: CN1C(CCC1=O)c1cccnc1

Synonyms:

• 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-
• 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
• 1-Methyl-5-(Pyridin-3-Yl)Pyrrolidin-2-One

1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one

CAS: 15569-85-4

Formula: C₁₀H₁₂N₂O

Color and Shape: Solid

Molecular weight: 176.2151

Ref: IN-DA001O46

rac-Cotinine

Controlled Product

CAS: 15569-85-4

Applications A major metabolite of Nicotine in humans. Carcinogen.
References Sugasawa, S., et al.: Pharma. Bull., et al.: 2, 39 (1954), Thompson, J.A., et al.: J. Chromatog., 231, 53 (1982); Seeman, J.I., et al.: J. Org. Chem., 51, 1548 (1986)

Formula: C₁₀H₁₂N₂O

Color and Shape: Neat

Molecular weight: 176.22

Ref: TR-C725004