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CAS 155716-06-6

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OKADAIC ACID AMMONIUM SALT

Description:
Okadaic acid ammonium salt is a derivative of okadaic acid, a polyether compound originally isolated from marine organisms, particularly certain species of dinoflagellates. This compound is known for its potent inhibitory effects on protein phosphatases, specifically protein phosphatase 1 and 2A, which play crucial roles in various cellular processes, including cell signaling and regulation of the cell cycle. The ammonium salt form enhances its solubility in aqueous solutions, making it more accessible for biological studies. Okadaic acid and its derivatives are often used in research to investigate cellular signaling pathways and have implications in toxicology, particularly concerning marine biotoxins. The compound is also of interest in pharmacological research due to its potential effects on cancer cell proliferation and apoptosis. However, it is important to handle this substance with care, as it can be toxic and has been associated with harmful algal blooms that affect marine life and human health.
Formula:C44H71NO13
InChI:InChI=1/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1
Synonyms:
  • Okadaic Acid Ammonium
  • Okadaic Acid Ammonium Salt, Prorocentrum Concavum
  • 9,10-Deepithio-9,10-Didehydroacanthifolicin
  • Okadaic Acid Ammonium From Prorocentrum Concavum
  • Okadaic Acid Ammonium Salt (High Purity)
  • ammonium (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(1R,2E)-3-[(2R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-1-methylprop-2-en-1-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoate
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