CAS 155836-78-5

(2R,5S)-2,5-Dimethyl-1-(2-propen-1-yl)piperazine

Description:

(2R,5S)-2,5-Dimethyl-1-(2-propen-1-yl)piperazine is a chemical compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. The specific stereochemistry indicated by the (2R,5S) notation suggests that the compound has specific spatial arrangements of its substituents, which can significantly influence its chemical behavior and biological activity. The presence of two methyl groups at the 2 and 5 positions of the piperazine ring, along with a propenyl group at the 1 position, contributes to its unique reactivity and potential interactions with biological targets. This compound may exhibit properties typical of piperazine derivatives, such as potential pharmacological activities, including effects on neurotransmitter systems. Its structural features suggest it could be of interest in medicinal chemistry, particularly in the development of new therapeutic agents. However, detailed studies would be necessary to fully elucidate its properties, including solubility, stability, and specific biological activities.

Formula: C₉H₁₈N₂

InChI: InChI=1S/C9H18N2/c1-4-5-11-7-8(2)10-6-9(11)3/h4,8-10H,1,5-7H2,2-3H3/t8-,9+/m0/s1

InChI key: InChIKey=VKUXNUOPPQWDMV-DTWKUNHWSA-N

SMILES: C(C=C)N1[C@H](C)CN[C@@H](C)C1

Synonyms:

• (2R,5S)-1-Allyl-2,5-dimethylpiperazine
• (2R,5S)-2,5-Dimethyl-1-(2-propen-1-yl)piperazine
• (2R,5S)-2,5-Dimethyl-1-Prop-2-En-1-Ylpiperazine
• Piperazine, 2,5-dimethyl-1-(2-propen-1-yl)-, (2R,5S)-
• Piperazine, 2,5-dimethyl-1-(2-propenyl)-, (2R,5S)-
• Piperazine, 2,5-dimethyl-1-(2-propenyl)-, (2R-trans)-

(-)-(2R,5S)-1-Allyl-2,5-dimethylpiperazine

Controlled Product

CAS: 155836-78-5

Applications (-)-(2R,5S)-1-Allyl-2,5-dimethylpiperazine (cas# 155836-78-5) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bishop, M., et al.: Bioorg. Med. Chem. Lett., 5, 1311 (1995), Bishop, M., et al.: J. Med. Chem., 46, 623 (2003),

Formula: C₉H₁₈N₂

Color and Shape: Neat

Molecular weight: 154.26

Ref: TR-A552540

(-)-(2R,5S)-1-Allyl-2,5-dimethylpiperazine

CAS: 155836-78-5

(-)-(2R,5S)-1-Allyl-2,5-dimethylpiperazine is a novel analog of benzyl alcohols that binds to the delta opioid receptor. The compound was found to be an agonist in vitro and in vivo. It showed no affinity for other opioid receptors or for the benzodiazepine receptor. (-)-(2R,5S)-1-Allyl-2,5-dimethylpiperazine was found to have high affinity for the human cloned delta opioid receptor with a Ki value of 0.6 nM. This compound is also a potent alkylate inhibitor with an IC50 of 6 microM against ethoxy radical formation and an IC50 of 25 microM against lipid peroxidation induced by H2O2.

Formula: C₉H₁₈N₂

Purity: Min. 95%

Molecular weight: 154.25 g/mol

Ref: 3D-FA17303