17(R)-HDOHE, or 17-hydroxydocosahexaenoic acid, is a bioactive lipid derived from docosahexaenoic acid (DHA), an omega-3 fatty acid. This compound is characterized by its role as a signaling molecule in various physiological processes, particularly in the central nervous system and immune response. It exhibits anti-inflammatory properties and is involved in neuroprotection, making it of interest in research related to neurodegenerative diseases and inflammatory conditions. The stereochemistry of the molecule, indicated by the (R) configuration, plays a crucial role in its biological activity and interaction with receptors. 17(R)-HDOHE is typically studied in the context of its potential therapeutic applications, including its effects on cell signaling pathways and its influence on gene expression. Its presence in biological systems highlights the importance of omega-3 fatty acids in maintaining health and preventing disease. As a relatively specific compound, it is often analyzed in biochemical and pharmacological studies to understand its mechanisms of action and potential benefits in health and disease management.

Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-
treated experimental animals. 17(R)-
HDHA is the primary oxygenation product of DHA when exposed to aspirin-
inhibited cyclooxygenase-
2. 17(R)-
HDHA serves as a precursor to resolvins and has intrinsic biological activity, such as the inhibition of TNFα-
induced IL-
1β expression in human glioma cells.

17(R)-HDOHE

155976-53-7: 17(R)-HDOHE, or 17-hydroxydocosahexaenoic acid, is a bioactive lipid derived from docosahexaenoic acid (DHA), an omega-3 fatty acid. This compound is characterized by its role as a signaling molecule in various physiological processes, particularly in the central nervous system and immune response. It exhibits anti-inflammatory properties and is involved in neuroprotection, making it of interest in research related to neurodegenerative diseases and inflammatory conditions. The stereochemistry of the molecule, indicated by the (R) configuration, plays a crucial role in its biological activity and interaction with receptors. 17(R)-HDOHE is typically studied in the context of its potential therapeutic applications, including its effects on cell signaling pathways and its influence on gene expression. Its presence in biological systems highlights the importance of omega-3 fatty acids in maintaining health and preventing disease. As a relatively specific compound, it is often analyzed in biochemical and pharmacological studies to understand its mechanisms of action and potential benefits in health and disease management.

17(R)-HDHA

<p>Resolvins, aspirin-derived from DHA, are anti-inflammatory, inhibiting cytokines in human glioma cells.</p>

CAS 155976-53-7

17(R)-HDOHE

17(R)-HDHA

Ref: IN-DA001OEA

17(R)-HDHA

Ref: TM-T36042

17(R)-hydroxy-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid

Ref: 48-14-2272