CAS 156-51-4

Phenelzine sulfate

Description:

Phenelzine sulfate is a chemical compound that serves primarily as a monoamine oxidase inhibitor (MAOI) and is used in the treatment of depression and anxiety disorders. It is a hydrazine derivative, characterized by its ability to inhibit the enzyme monoamine oxidase, which is responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This inhibition leads to increased levels of these neurotransmitters, contributing to its antidepressant effects. Phenelzine sulfate is typically administered in its sulfate salt form, which enhances its solubility and bioavailability. The compound is known for its potential side effects, including dietary restrictions due to the risk of hypertensive crises when consumed with tyramine-rich foods. Additionally, it may interact with other medications, necessitating careful monitoring by healthcare professionals. Its chemical structure includes a phenyl ring and a hydrazine group, contributing to its pharmacological properties. Overall, Phenelzine sulfate is a significant agent in psychopharmacology, particularly for treatment-resistant depression.

Formula: C₈H₁₂N₂·H₂O₄S

InChI: InChI=1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

InChI key: InChIKey=RXBKMJIPNDOHFR-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.C(CNN)C1=CC=CC=C1

Synonyms:

• (1-Phenylethyl)Hydrazinium Hydrogen Sulfate
• (2-Phenylethyl)Hydrazine
• (2-Phenylethyl)Hydrazine Sulfate (1:1)
• (2-Phenylethyl)hydrazine dihydrogen sulfate
• (β-Phenylethyl)hydrazine dihydrogen sulfate
• (β-Phenylethyl)hydrazine sulfate
• 2-Phenethylhydrazine sulfate
• Estinerval
• Fenelzin
• Hydrazine, (2-phenylethyl)-, sulfate (1:1)
• Hydrazine, phenethyl-, sulfate (1:1)
• Kalgan
• Mao-rem
• NSC 170957
• Nardelzine
• Nardil
• Phenalzine dihydrogen sulfate
• Phenelzine Hydrogen Sulphate
• Phenelzine acid sulfate
• Phenelzine bisulfate
• Phenelzine dihydrogen sulfate
• Phenelzine hydrogen sulfate
• Phenethylhydrazine Sulfate
• Stinerval

Phenelzine Sulfate

CAS: 156-51-4

Color and Shape: Neat

Ref: 61-FOR1472.00

Phenelzine sulfate

CAS: 156-51-4

Phenelzine sulfate

Formula: C₈H₁₂N₂H₂SO₄

Purity: 99.4%

Color and Shape: White. To. Off-White

Molecular weight: 234.06743

Ref: 47-1166

Phenelzine Sulfate

CAS: 156-51-4

Aromatic organic derivatives of hydrazine or of hydroxylamine

Formula: C₈H₁₂N₂·H₂SO₄

Color and Shape: White Yellow Powder

Molecular weight: 136.10005

Ref: 45-1517006

Phenelzine sulfate

CAS: 156-51-4

Phenelzine sulfate is a non-selective and irreversible inhibitor of monoamine oxidase (MAOI), and with antidepressant and anxiolytic.

Formula: C₈H₁₄N₂O₄S

Purity: 98.38% - 99.83%

Color and Shape: Solid

Molecular weight: 234.27

Ref: TM-T12441

Phenelzine (sulfate)

CAS: 156-51-4

Formula: C₈H₁₄N₂O₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 234.2728

Ref: IN-DA001OF3

Phenelzine sulfate salt

CAS: 156-51-4

Formula: C₈H₁₂N₂·H₂SO₄

Purity: (Titration) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 234.27

Ref: 7W-GK3664

Phenelzine sulfate

CAS: 156-51-4

Phenelzine sulfate

Purity: ≥98%

Molecular weight: 234.27g/mol

Ref: 54-BUP11750

Phenelzine Sulfate

CAS: 156-51-4

Formula: C₈H₁₂N₂·H₂SO₄

Color and Shape: White To Off-White Solid

Molecular weight: 136.20 98.08

Ref: 4Z-P-256001

Phenylethylhydrazine Sulfate

CAS: 156-51-4

Phenylethylhydrazine Sulfate

Purity: 98%

Molecular weight: 234.27g/mol

Ref: 54-OR1025679

Phenelzine-d5 Sulfate (phenyl-d5)

CAS: 1219798-40-9, 156-51-4

Formula: C₆D₅CH₂CH₂NHNH₂H₂SO₄

Purity: 99 atom % D

Color and Shape: White Solid

Molecular weight: 239.09881

Ref: 3U-D5893

Phenelzine Sulfate

Controlled Product

CAS: 156-51-4

Formula: C₈H₁₂N₂·H₂O₄S

Color and Shape: Neat

Molecular weight: 234.27

Ref: 86-MM1472.00

Phenelzine Sulfate

Controlled Product

CAS: 156-51-4

Applications A hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References MacKenzie, E.M. et al.: Neurochem. Res., 33, 430 (2008); Chiche, F. et al.: Mol. Pharmacol., 75, 1052 (2009); McKenna, K.F, et al.: J. Neural Trans., 41, 115 (1994);

Formula: C₈H₁₂N₂·H₂O₄S

Color and Shape: Neat

Molecular weight: 234.27

Ref: TR-P295900

Phenelzine sulfate

Controlled Product

CAS: 156-51-4

Phenelzine sulfate is a non-selective, irreversible inhibitor of the enzyme monoamine oxidase (MAO). It has been shown to inhibit 5-HT2 receptors in an experimental model. Phenelzine sulfate has been used as a pharmacological agent in the treatment of depression and anxiety disorders. Phenelzine sulfate inhibits the activity of other drugs metabolized by MAO, such as tricyclic antidepressants and beta-blockers. It also inhibits atherosclerotic lesion formation and neuronal death induced by amyloid peptide in mice.

Formula: C₈H₁₄N₂O₄S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 234.27 g/mol

Ref: 3D-FP26874

PHENELZINE SULFATE

CAS: 156-51-4

Formula: C₈H₁₄N₂O₄S

Purity: 99%

Molecular weight: 234.27

Ref: 10-F470205