CAS 156-51-4: Phenelzine sulfate
Description:Phenelzine sulfate is a chemical compound that serves primarily as a monoamine oxidase inhibitor (MAOI) and is used in the treatment of depression and anxiety disorders. It is a hydrazine derivative, characterized by its ability to inhibit the enzyme monoamine oxidase, which is responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This inhibition leads to increased levels of these neurotransmitters, contributing to its antidepressant effects. Phenelzine sulfate is typically administered in its sulfate salt form, which enhances its solubility and bioavailability. The compound is known for its potential side effects, including dietary restrictions due to the risk of hypertensive crises when consumed with tyramine-rich foods. Additionally, it may interact with other medications, necessitating careful monitoring by healthcare professionals. Its chemical structure includes a phenyl ring and a hydrazine group, contributing to its pharmacological properties. Overall, Phenelzine sulfate is a significant agent in psychopharmacology, particularly for treatment-resistant depression.
Formula:C8H12N2·H2O4S
InChI:InChI=1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)
InChI key:InChIKey=RXBKMJIPNDOHFR-UHFFFAOYSA-N
SMILES:O=S(=O)(O)O.NNCCC=1C=CC=CC1
- Synonyms:
- (1-Phenylethyl)Hydrazinium Hydrogen Sulfate
- (2-Phenylethyl)Hydrazine
- (2-Phenylethyl)Hydrazine Sulfate (1:1)
- (2-Phenylethyl)hydrazine dihydrogen sulfate
- (β-Phenylethyl)hydrazine dihydrogen sulfate
- (β-Phenylethyl)hydrazine sulfate
- 2-Phenethylhydrazine sulfate
- Estinerval
- Fenelzin
- Hydrazine, (2-phenylethyl)-, sulfate (1:1)
- See more synonyms
- Hydrazine, phenethyl-, sulfate (1:1)
- Kalgan
- Mao-rem
- NSC 170957
- Nardelzine
- Nardil
- Phenalzine dihydrogen sulfate
- Phenelzine Hydrogen Sulphate
- Phenelzine acid sulfate
- Phenelzine bisulfate
- Phenelzine dihydrogen sulfate
- Phenelzine hydrogen sulfate
- Phenethylhydrazine Sulfate
- Stinerval
- W 1544A