CAS 156-81-0

2,4-Diaminopyrimidine

Description:

2,4-Diaminopyrimidine is an organic compound characterized by its pyrimidine ring structure, which features two amino groups at the 2 and 4 positions. This compound is typically a white to off-white crystalline solid and is soluble in water and various organic solvents. It has a molecular formula of C4H6N4 and a relatively low molecular weight. 2,4-Diaminopyrimidine is known for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of antifolate drugs. The presence of amino groups makes it a versatile building block in organic synthesis, allowing for various chemical modifications. Additionally, it exhibits biological activity, which has led to its investigation in medicinal chemistry. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Overall, 2,4-Diaminopyrimidine is a significant compound in both industrial and research applications due to its chemical properties and biological relevance.

Formula: C₄H₆N₄

InChI: InChI=1/C4H6N4/c5-3-1-2-7-4(6)8-3/h1-2H,(H4,5,6,7,8)

InChI key: InChIKey=YAAWASYJIRZXSZ-UHFFFAOYSA-N

SMILES: NC1=NC(N)=NC=C1

Synonyms:

• 2,4-Diamino pyrimidine
• 2,4-Pyrimidinediamine
• 3-Morpholinosydnoneimine HCl
• NSC 30856
• Pyrimidine, 2,4-diamino-
• Pyrimidine-2,4-Diamine
• Pyrimidine-2,4-Diyldiamine
• 2,4-Diaminopyrimidine
• 2,4-PYRIMIDINEDIAMINE 98+%
• 2,6-DIAMINOPYRIMIDINE
• Diaminopyrimidine
• 2,4-Diaminopyrimidine (sulphate)
• DAP
• 2,4-DIAMINOPYRIMIDINE 97%

2,4-Diaminopyrimidine

CAS: 156-81-0

Formula: C₄H₆N₄

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 110.12

Ref: 3B-D2120

2,4-Diaminopyrimidine

CAS: 156-81-0

Formula: C₄H₆N₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 110.1172

Ref: IN-DA00HYCZ

Pyrimidine-2,4-diamine

CAS: 156-81-0

Pyrimidine-2,4-diamine

Formula: C₄H₆N₄

Purity: 96%

Color and Shape: faint beige powder

Molecular weight: 110.12g/mol

Ref: 54-OR30933

2,4-Diaminopyrimidine

CAS: 156-81-0

Formula: C₄H₆N₄

Molecular weight: 110.12

Ref: 4Z-P-212028

2,4-Diaminopyrimidine

CAS: 156-81-0

2,4-Diaminopyrimidine is a potent inhibitor of protein kinases with selectivity for ATP-dependent enzymes. It inhibits the activity of the epidermal growth factor receptor (EGFR). The effectiveness of 2,4-diaminopyrimidine against colorectal adenocarcinoma cells has been demonstrated in vitro and in vivo. The drug has been shown to inhibit EGFR phosphorylation and downstream signaling pathways, which may be responsible for its ability to induce apoptosis in these cancer cells. 2,4-Diaminopyrimidine has also been shown to have anti-inflammatory effects by inhibiting the production of proinflammatory cytokines and chemokines. This drug is used in clinical studies as an anti-infective agent against infectious diseases such as tuberculosis, malaria, and dengue fever.

Formula: C₄H₆N₄

Purity: Min. 97.5 Area-%

Color and Shape: Powder

Molecular weight: 110.12 g/mol

Ref: 3D-FD10677

Pyrimidine-2,4-diamine

CAS: 156-81-0

Formula: C₄H₆N₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 110.12

Ref: 10-F079382