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CAS 156006-28-9

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3,4,5-trifluorophenylmagnesium bromide

Description:
3,4,5-Trifluorophenylmagnesium bromide is an organometallic compound belonging to the class of Grignard reagents, characterized by the presence of a trifluorophenyl group bonded to a magnesium atom, with bromide serving as the counterion. This compound is typically formed by the reaction of 3,4,5-trifluorobromobenzene with magnesium in an anhydrous ether solvent. It is highly reactive, particularly with moisture and protic solvents, leading to the release of hydrocarbons and the formation of corresponding alcohols upon hydrolysis. The trifluoromethyl groups enhance the electrophilicity of the phenyl ring, making it a valuable intermediate in organic synthesis, particularly in the formation of carbon-carbon bonds. Additionally, the presence of fluorine atoms can influence the electronic properties and reactivity of the compound, making it useful in various applications, including pharmaceuticals and agrochemicals. Due to its reactivity, it must be handled under inert atmospheres to prevent decomposition and unwanted side reactions.
Formula:C6H2BrF3Mg
InChI:InChI=1/C6H2F3.BrH.Mg/c7-4-2-1-3-5(8)6(4)9;;/h2-3H;1H;/q;;+1/p-1/rC6H2BrF3Mg/c7-11-3-1-4(8)6(10)5(9)2-3/h1-2H
SMILES:C1=CC(=C(C(C=1)F)F)F.Br.[Mg]
Synonyms:
  • Bromo-(3,4,5-Trifluorophenyl)Magnesium
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