CAS: 1561178-17-3 - 5-Bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Formula: C₂₈H₄₀BrN₇O₄

InChI: InChI=1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,15-16,20,22-23,26,37-38H,6,11-12,14H2,1-5H3,(H2,30,32,33)(H2,31,34,39)/t20-,22-,23-,26-/m1/s1

InChI key: InChIKey=IQCKJUKAQJINMK-HUBRGWSESA-N

SMILES: O=C(NC1=CC=C(C=C1)C(C)(C)C)NCCCN(CC2OC(N3C=C(Br)C=4C(=NC=NC43)N)C(O)C2O)C(C)C

Synonyms:

• 5-Bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• SGC 0946
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-

7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-

CAS: 1561178-17-3

• Formula: C₂₈H₄₀BrN₇O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 618.5657

SGC0946

CAS: 1561178-17-3

SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill …

• Formula: C₂₈H₄₀BrN₇O₄
• Purity: 98% - 99.82%
• Color and Shape: Solid
• Molecular weight: 618.57

SGC-0946

CAS: 1561178-17-3

Applications SGC0946 is a potent DOT1L methyltransferase inhbiitor used in the treatment of leukemia seen …

• Formula: C₂₈H₄₀BrN₇O₄
• Color and Shape: Neat
• Molecular weight: 618.57

SGC0946

CAS: 1561178-17-3

SGC0946 is a methyltransferase inhibitor that inhibits the methylation of DNA by inhibiting the activity …

• Formula: C₂₈H₄₀BrN₇O₄
• Purity: Min. 95%
• Molecular weight: 618.57 g/mol

SGC0946

CAS: 1561178-17-3

• Molecular weight: 618.57g/mol