Alvimopan is a selective antagonist of the μ-opioid receptor, primarily used to manage postoperative ileus, a condition characterized by a temporary cessation of bowel activity following surgery. The enantiomer of Alvimopan refers to one of the two mirror-image forms of the molecule, which can exhibit different pharmacological properties. The substance is characterized by its ability to block the effects of opioids on the gastrointestinal tract without affecting analgesic effects in the central nervous system. This selectivity is crucial for its therapeutic application, as it helps restore bowel function while minimizing the risk of opioid-related side effects. Alvimopan is typically administered orally and has a specific pharmacokinetic profile, including a relatively short half-life. Its safety profile is generally favorable, but it is contraindicated in patients with certain conditions, such as severe hepatic impairment. Overall, Alvimopan enantiomer plays a significant role in postoperative care, enhancing recovery by promoting gastrointestinal motility.

Alvimopan Enantiomer

156130-44-8: Alvimopan is a selective antagonist of the μ-opioid receptor, primarily used to manage postoperative ileus, a condition characterized by a temporary cessation of bowel activity following surgery. The enantiomer of Alvimopan refers to one of the two mirror-image forms of the molecule, which can exhibit different pharmacological properties. The substance is characterized by its ability to block the effects of opioids on the gastrointestinal tract without affecting analgesic effects in the central nervous system. This selectivity is crucial for its therapeutic application, as it helps restore bowel function while minimizing the risk of opioid-related side effects. Alvimopan is typically administered orally and has a specific pharmacokinetic profile, including a relatively short half-life. Its safety profile is generally favorable, but it is contraindicated in patients with certain conditions, such as severe hepatic impairment. Overall, Alvimopan enantiomer plays a significant role in postoperative care, enhancing recovery by promoting gastrointestinal motility.

ent-Alvimopan

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CAS 156130-44-8

Alvimopan Enantiomer

ent-Alvimopan

Ref: TR-A575675

Ent-alvimopan

Ref: 3D-GGA13044

(2R,3S,4S)-Alvimopan

Ref: ST-EA-CP-A127003