CAS 156137-99-4

Rapacuronium bromide

Description:

Rapacuronium bromide is a neuromuscular blocking agent primarily used in anesthesia to facilitate intubation and provide muscle relaxation during surgical procedures. It is classified as a non-depolarizing neuromuscular blocker, which means it works by competitively inhibiting the action of acetylcholine at the neuromuscular junction, leading to muscle paralysis. The substance has a rapid onset of action and a relatively short duration of effect, making it suitable for procedures requiring quick muscle relaxation. Chemically, rapacuronium is characterized by its quaternary ammonium structure, which contributes to its pharmacological properties. It is typically administered intravenously and is metabolized primarily by the liver, with excretion occurring through the kidneys. Due to its specific action and pharmacokinetics, rapacuronium bromide is utilized in controlled settings, and its use may be accompanied by monitoring for potential side effects, such as cardiovascular effects or allergic reactions. As with all neuromuscular blockers, careful dosing and patient monitoring are essential to ensure safety and efficacy during surgical procedures.

Formula: C₃₇H₆₁N₂O₄·Br

InChI: InChI=1S/C37H61N2O4.BrH/c1-6-20-39(21-12-9-13-22-39)32-24-30-28-15-14-27-23-33(42-26(3)40)31(38-18-10-8-11-19-38)25-37(27,5)29(28)16-17-36(30,4)35(32)43-34(41)7-2;/h6,27-33,35H,1,7-25H2,2-5H3;1H/q+1;/p-1/t27-,28+,29-,30-,31-,32-,33-,35-,36-,37-;/m0./s1

InChI key: InChIKey=LVQTUXZKLGXYIU-GWSNJHLMSA-M

SMILES: C(C=C)[N@@+]1(CCCCC1)[C@@H]2[C@H](OC(CC)=O)[C@]3(C)[C@@](C2)([C@]4([C@](CC3)([C@]5(C)[C@@](CC4)(C[C@H](OC(C)=O)[C@H](C5)N6CCCCC6)[H])[H])[H])[H].[Br-]

Synonyms:

• (2Beta,3Alpha,5Alpha,16Beta,17Beta)-3-(Acetyloxy)-2-Piperidin-1-Yl-17-(Propanoyloxy)-16-(1-Prop-2-En-1-Ylpiperidinium-1-Yl)Androstane Bromide
• (2Beta,3Alpha,5Alpha,8Xi,9Xi,14Xi,16Beta,17Beta)-3-(Acetyloxy)-2-(Piperidin-1-Yl)-17-(Propanoyloxy)-16-[1-(Prop-2-En-1-Yl)Piperidinium-1-Yl]Androstane Bromide
• Org 9487
• Piperidinium, 1-[(2β,3α,5α,16β,17β)-3-(acetyloxy)-17-(1-oxopropoxy)-2-(1-piperidinyl)androstan-16-yl]-1-(2-propen-1-yl)-, bromide (1:1)
• Piperidinium, 1-[(2β,3α,5α,16β,17β)-3-(acetyloxy)-17-(1-oxopropoxy)-2-(1-piperidinyl)androstan-16-yl]-1-(2-propenyl)-, bromide
• Rapacuronium Bromide
• Raplon

Rapacuronium Bromide

Controlled Product

CAS: 156137-99-4

Formula: C₃₇H₆₁N₂O₄·Br

Color and Shape: Neat

Molecular weight: 677.795

Ref: TR-R124050

Rapacuronium bromide

CAS: 156137-99-4

Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.

Formula: C₃₇H₆₁BrN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 677.8

Ref: TM-T12690