CAS 15639-50-6: Safingol

Description: Safingol, with the CAS number 15639-50-6, is a synthetic sphingolipid analog that has garnered interest in biomedical research, particularly in the context of cancer therapy and neuroprotection. It is characterized by its ability to inhibit sphingosine kinase, an enzyme involved in the metabolism of sphingolipids, which plays a crucial role in cell signaling and apoptosis. Safingol is typically presented as a white to off-white solid and is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. Its mechanism of action involves the modulation of ceramide and sphingosine levels, influencing cell growth and survival pathways. Due to its properties, Safingol has been studied for its potential therapeutic applications in various malignancies and neurodegenerative diseases. However, further research is necessary to fully elucidate its pharmacological effects and therapeutic efficacy in clinical settings.

Formula: C₁₈H₃₉NO₂

InChI: InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18-/m0/s1

InChI key: InChIKey=OTKJDMGTUTTYMP-ROUUACIJSA-N

SMILES: OCC(N)C(O)CCCCCCCCCCCCCCC

Synonyms:

• (-)-threo-Dihydrosphingosine
• (2S,3S)-2-Amino-1,3-octadecanediol
• (2S,3S)-2-aminooctadecane-1,3-diol
• 1,3-Octadecanediol, 2-amino-, (2S,3S)-
• 1,3-Octadecanediol, 2-amino-, <span class="text-smallcaps">L</span>-threo-
• 1,3-Octadecanediol, 2-amino-, [S-(R*,R*)]-
• <span class="text-smallcaps">L</span>-(-)-threo-Sphinganine
• <span class="text-smallcaps">L</span>-Threo-Dihydrosphingosine
• <span class="text-smallcaps">L</span>-threo-2-Amino-1,3-octadecanediol
• <span class="text-smallcaps">L</span>-threo-Safingol
• Safingol
• Spc 100270
• 1,3-Octadecanediol, 2-amino-, L-threo-
• L-threo-2-Amino-1,3-octadecanediol

1,3-Octadecanediol, 2-amino-, (2S,3S)-

CAS: 15639-50-6

• Formula: C₁₈H₃₉NO₂
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 301.5078

L-threo-Dihydrosphingosine

CAS: 15639-50-6

• Formula: C₁₈H₃₉NO₂
• Molecular weight: 301.51

L-threo-Dihydrosphingosine

CAS: 15639-50-6

• Formula: C18H39NO2
• Purity: >99%
• Color and Shape: Solid
• Molecular weight: 301.51

L-threo-Dihydrosphingosine

CAS: 15639-50-6

• Formula: C₁₈H₃₉NO₂
• Color and Shape: Neat
• Molecular weight: 301.508

L-threo-Dihydrosphingosine

CAS: 15639-50-6

L-threo-Dihydrosphingosine is a sphingoid that belongs to the group of sphingolipids. It is formed from …

• Formula: C₁₈H₃₉NO₂
• Purity: Min. 95%
• Molecular weight: 301.51 g/mol