CAS 156458-93-4

5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol

Description:

5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol, with the CAS number 156458-93-4, is a chemical compound that belongs to the class of dibenzo[a,d]cycloheptenes. This compound features a complex polycyclic structure, characterized by the presence of a cyclopropyl group and a piperidinyl substituent, which contribute to its unique chemical properties. It is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The presence of the hydroxyl (-OH) group indicates that it can participate in hydrogen bonding, which may influence its reactivity and interactions with biological systems. This compound has garnered interest in medicinal chemistry, particularly for its potential pharmacological activities, although specific biological effects and mechanisms of action would require further investigation. As with many organic compounds, safety data should be consulted to understand its handling and toxicity profiles.

Formula: C₂₃H₂₅NO

InChI: InChI=1S/C23H25NO/c25-23(18-12-13-18)20-10-4-2-8-17(20)16-22(24-14-6-1-7-15-24)19-9-3-5-11-21(19)23/h2-5,8-11,16,18,25H,1,6-7,12-15H2

InChI key: InChIKey=UPLBRZUWLDDXKY-UHFFFAOYSA-N

SMILES: OC1(C=2C(C(=CC=3C1=CC=CC3)N4CCCCC4)=CC=CC2)C5CC5

Synonyms:

• 5H-Dibenzo[a,d]cyclohepten-5-ol, 5-cyclopropyl-10-(1-piperidinyl)-, (±)-
• 5H-Dibenzo[a,d]cyclohepten-5-ol, 5-cyclopropyl-10-(1-piperidinyl)-
• 5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol

5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol

Controlled Product

CAS: 156458-93-4

Applications 5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Formula: C₂₃H₂₅NO

Color and Shape: Neat

Molecular weight: 331.451

Ref: TR-C417355