CAS 156592-92-6

2',3'-DITHIOURIDINE

Description:

2',3'-Dithiouridine is a modified nucleoside that features a uridine backbone with two sulfur atoms replacing the oxygen atoms at the 2' and 3' positions of the ribose sugar. This modification imparts unique chemical properties, enhancing its stability against enzymatic degradation and influencing its biological activity. The presence of sulfur atoms can also affect hydrogen bonding and base pairing, potentially altering the nucleoside's interactions within RNA structures. 2',3'-Dithiouridine has been studied for its role in various biochemical processes, including its potential as an antiviral agent and its involvement in RNA metabolism. Its structural modifications may also contribute to its ability to modulate cellular responses and influence gene expression. The compound is typically characterized by its solubility in polar solvents and its reactivity with electrophiles due to the presence of sulfur. Overall, 2',3'-Dithiouridine represents an important tool in molecular biology and medicinal chemistry, offering insights into nucleoside function and therapeutic applications.

Formula: C₉H₁₂N₂O₄S₂

InChI: InChI=1/C9H12N2O4S2/c12-3-4-6(16)7(17)8(15-4)11-2-1-5(13)10-9(11)14/h1-2,4,6-8,12,16-17H,3H2,(H,10,13,14)/t4-,6+,7?,8-/m1/s1

2’,3’-Dithiouridine

CAS: 156592-92-6

Formula: C₉H₁₂N₂O₄S₂

Color and Shape: Solid

Molecular weight: 276.3326

Ref: IN-DA001OTP

2’,3’-Dithiouridine

Controlled Product

CAS: 156592-92-6

Applications 2’,3’-Dithiouridine (cas# 156592-92-6) is a compound useful in organic synthesis.

Formula: C₉H₁₂N₂O₄S₂

Color and Shape: Neat

Molecular weight: 276.33

Ref: TR-D494375

2',3'-Dithiouridine

CAS: 156592-92-6

2',3'-Dithiouridine is a triamide that is synthesized from uridine and chloroacetic acid. The dimeric form of this compound has been shown to be the most stable and yields are high. 2',3'-Dithiouridine can be prepared by the reaction of uridine with chloroacetyl chloride in DMSO at room temperature. The disulfide linkage between the two thiouridines is stereospecifically oriented in a cis conformation. The synthesis of 2',3'-dithiouridine from uridine and chloroacetic acid is achieved by an efficient procedure that gives high yields. This synthetic pathway also produces a crystalline, cyclic, sodium salt form of 2',3',4'-trihydroxypentane-1,5-dione that has not been previously reported.

Formula: C₉H₁₂N₂O₄S₂

Purity: Min. 95%

Molecular weight: 276.33 g/mol

Ref: 3D-ND22570