CAS 156601-79-5
:Nepaprazole
Description:
Nepaprazole, identified by its CAS number 156601-79-5, is a chemical compound that belongs to the class of proton pump inhibitors (PPIs). These substances are primarily used to reduce gastric acid secretion and are commonly employed in the treatment of conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. Nepaprazole functions by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased acid production. The compound is characterized by its ability to provide long-lasting effects on acid secretion, making it effective for managing acid-related disorders. In terms of its physical properties, Nepaprazole is typically a white to off-white crystalline powder, which is soluble in organic solvents but has limited solubility in water. Its pharmacokinetics involve metabolism primarily in the liver, with excretion occurring through the urine. As with other PPIs, potential side effects may include gastrointestinal disturbances and, with long-term use, an increased risk of certain infections and nutrient malabsorption.
Formula:C18H19N3O2S
InChI:InChI=1/C18H19N3O2S/c1-23-15-10-11-19-17-12(15)6-2-5-9-16(17)24(22)18-20-13-7-3-4-8-14(13)21-18/h3-4,7-8,10-11,16H,2,5-6,9H2,1H3,(H,20,21)/t16-,24+/m1/s1
Synonyms:- Nepaprazole [INN]
- (+-)-(9R*)-9-((SS*)-2-Benzimidazolylsulfinyl)-6,7,8,9-tetrahydro-4-methoxy-5H-cyclohepta(b)pyridine
- Unii-Uzt71Bq5Oo
- 9-(1H-benzimidazol-2-ylsulfinyl)-4-methoxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine
- (9R)-9-[(S)-1H-benzimidazol-2-ylsulfinyl]-4-methoxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
Nepaprazole
CAS:<p>Nepaprazole (TY-11345) is a potent proton pump inhibitor; IC50: 5.8µM at pH 6.0, 9.9µM at pH 7.4. Better inhibition in weak acid.</p>Formula:C18H19N3O2SPurity:98%Color and Shape:SolidMolecular weight:341.43
