CAS 156620-46-1

amythiamicin D

Description:

Amythiamicin D is a member of the amythiamicin family, which are natural products known for their antibiotic properties. This compound is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. It exhibits potent antimicrobial effects, particularly against certain strains of bacteria, making it of interest in pharmaceutical research. The compound's mechanism of action typically involves interference with bacterial protein synthesis, although specific pathways may vary. Amythiamicin D is often studied for its potential applications in treating infections, especially those caused by resistant bacterial strains. Additionally, its stability, solubility, and bioavailability are important factors that influence its efficacy as a therapeutic agent. As with many natural products, the extraction and purification processes can be challenging, and ongoing research aims to optimize these methods for better yield and application in medicinal chemistry. Overall, amythiamicin D represents a significant area of study within the field of antibiotic development.

Formula: C₄₃H₄₂N₁₂O₇S₆

InChI: InChI=1/C43H42N12O7S6/c1-17(2)30-41-51-26(15-67-41)39-48-23(12-64-39)33-20(8-9-21(46-33)38-52-27(16-65-38)43(61)62-7)37-49-25(14-63-37)35(59)47-22(10-28(56)44-6)40-55-32(19(5)68-40)36(60)54-31(18(3)4)42-50-24(13-66-42)34(58)45-11-29(57)53-30/h8-9,12-18,22,30-31H,10-11H2,1-7H3,(H,44,56)(H,45,58)(H,47,59)(H,53,57)(H,54,60)

Synonyms:

• methyl 2-{21-methyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25,35-di(propan-2-yl)-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decaazaheptacyclo[34.2.1.1~2,5~.1~12,15~.1~19,22~.1~26,29~.0~6,11~]tritetraconta-1(38),2(43),4,6,8,10,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl}-1,3-thiazole-4-carboxylate (non-preferred name)
• Amythiamicin D
• 4-Thiazolecarboxylic acid, 2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-(methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-, methyl ester
• 4-Thiazolecarboxylic acid, 2-[(11S,18S,28S)-10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-[2-(methylamino)-2-oxoethyl]-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido[3,2-a1][1,11,18,25,31,4,7,14,21]pentathiatetraazacyclotetratria...

Amythiamicin D

CAS: 156620-46-1

Amythiamicin D is a thiopeptide antibiotic that effectively inhibits the growth of various Gram-positive bacteria, but it is ineffective against Gram-negative bacteria such as Escherichia coli.

Formula: C₄₃H₄₂N₁₂O₇S₆

Color and Shape: Solid

Molecular weight: 1031.26

Ref: TM-TN9167