CAS 156620-47-2

amythiamicin C

Description:

Amythiamicin C is a complex chemical compound classified as a natural product, specifically a member of the thiazole antibiotic family. It is known for its potent antibacterial properties, particularly against certain Gram-positive bacteria. The molecular structure of amythiamicin C features a unique bicyclic core that includes thiazole and other functional groups, contributing to its biological activity. This compound is typically produced by specific strains of bacteria, such as those in the genus Streptomyces, through fermentation processes. Its mechanism of action often involves inhibition of protein synthesis, making it effective in combating bacterial infections. Additionally, amythiamicin C may exhibit cytotoxic effects, which has garnered interest in the field of cancer research. Due to its complex structure and biological significance, amythiamicin C is of interest in medicinal chemistry and pharmaceutical development, although its use may be limited by factors such as toxicity and resistance. Further studies are ongoing to explore its full potential and applications in medicine.

Formula: C₅₀H₅₀N₁₄O₉S₆

InChI: InChI=1/C50H50N14O9S6/c1-20(2)35-47-59-30(18-78-47)45-56-27(15-75-45)38-23(9-10-24(53-38)44-60-31(19-76-44)50(72)73-14-26-49(71)64-11-7-8-32(64)41(69)55-26)43-57-29(17-74-43)40(68)54-25(12-33(65)51-6)46-63-37(22(5)79-46)42(70)62-36(21(3)4)48-58-28(16-77-48)39(67)52-13-34(66)61-35/h9-10,15-21,25-26,32,35-36H,7-8,11-14H2,1-6H3,(H,51,65)(H,52,67)(H,54,68)(H,55,69)(H,61,66)(H,62,70)

Synonyms:

• 4-Thiazolecarboxylic acid, 2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-, (octahydro-1,4-dioxopyrrolo(1,2-a)pyrazin-3-yl)methyl ester
• (1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl)methyl 2-{21-methyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25,35-di(propan-2-yl)-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decaazaheptacyclo[34.2.1.1~2,5~.1~12,15~.1~19,22~.1~26,29~.0~6,11~]tritetraconta-1(38),2(43),4,6,8,10,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl}-1,3-thiazole-4-carboxylate (non-preferred name)
• Amythiamicin C
• 4-Thiazolecarboxylic acid, 2-[10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-[2-(methylamino)-2-oxoethyl]-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido[3,2-a1][1,11,18,25,31,4,7,14,21]pentathiatetraazacyclotetratriacontin-2-yl]-,...

Amythiamicin C

CAS: 156620-47-2

Amythiamicin C is an antimicrobial antibiotic effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and also exhibits activity against Plasmodium falciparum (the causative agent of malaria).

Formula: C₅₀H₅₀N₁₄O₉S₆

Color and Shape: Solid

Molecular weight: 1183.41

Ref: TM-TN9129