CAS 15671-27-9

Sulfitocobalamin

Description:

Sulfitocobalamin, with the CAS number 15671-27-9, is a derivative of vitamin B12, specifically a form of cobalamin that contains a sulfonate group. It is characterized by its complex cobalt-centered structure, which is essential for its biological activity. This compound is typically a reddish-purple crystalline solid, reflecting the characteristic color of cobalamin derivatives. Sulfitocobalamin is soluble in water, which facilitates its use in various biochemical applications, particularly in the treatment of vitamin B12 deficiency. Its stability can be influenced by factors such as pH and light exposure, making proper storage conditions crucial. In biological systems, sulfitocobalamin can participate in enzymatic reactions, contributing to processes like DNA synthesis and red blood cell formation. Additionally, it may serve as a source of bioavailable cobalt, which is vital for numerous enzymatic functions. Overall, sulfitocobalamin plays a significant role in nutrition and biochemistry, particularly in relation to cellular metabolism and energy production.

Formula: C₆₂H₈₉CoN₁₃O₁₇PS

InChI: InChI=1S/C62H90N13O14P.Co.H2O3S/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;1-4(2)3/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;(H2,1,2,3)/q;+3;/p-3

InChI key: InChIKey=IUJJHFFFUXMHFY-UHFFFAOYSA-K

SMILES: [O-](S(=O)O)[Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Synonyms:

• Cobalamin, sulfito-
• Cobalaminsulfonic acid
• Cobinamide, Co-(sulfito-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, hydroxide sulfite (1:1) (salt), dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, sulfite (1:1) (salt), dihydrogen phosphate (ester), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, sulfite (1:1) (salt), dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, sulfite phosphate, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Sulfiotcobalamine
• Sulfitocobalamin
• Vitamin B₁₂-sulfonic acid
• Cobinamide, Co-(sulfito-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3)
• Cobinamide, sulfite phosphate, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, hydroxide sulfite (1:1) (salt), dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, sulfite (1:1) (salt), dihydrogen phosphate (ester), 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole

Sulphitocobalamin

CAS: 15671-27-9

Formula: C₆₂H₈₈CoN₁₃O₁₄P·HO₃S

Molecular weight: 1329.38 81.07

Ref: 4Z-V-035003

Sulfitocobalamin Sodium Salt

CAS: 15671-27-9

Applications Sulfitocobalamin Sodium Salt is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate (H826800); a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950); Friedrich, W., et al.: Vitamins, 837 (1988); Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993)

Formula: C₆₂H₈₈CoN₁₃NaO₁₇PS

Color and Shape: Neat

Molecular weight: 1432.4

Ref: TR-S699360

Sulfitocobalamin sodium salt

CAS: 15671-27-9

Sulfitocobalamin sodium salt is a bacterial strain that is used as a probiotic. It has been shown to be biocompatible and can be used with human liver cells in laboratory studies. Sulfitocobalamin sodium salt is also effective in treating bowel disease, because it reduces the inflammatory response by inhibiting pro-inflammatory cytokine production and preventing the damage of mucosal cells. Sulfitocobalamin sodium salt has been shown to inhibit growth of infectious bacteria, such as Salmonella enterica serovar Typhimurium and Helicobacter pylori, which cause diseases like hepatitis and corrinosis. The molecule also has biological properties that are used for the treatment of inflammation, ulcerative colitis, and other diseases caused by infectious agents.

Formula: C₆₂H₈₈CoN₁₃NaO₁₇PS

Purity: Min. 95%

Molecular weight: 1,432.4 g/mol

Ref: 3D-FS173315

Sulphitocobalamin

CAS: 15671-27-9

Formula: C₆₂H₈₈CoN₁₃O₁₄PHO₃S

Molecular weight: 1329.38 : 81.07

Ref: ST-EA-CP-H13003