CAS 156715-14-9

6-O-Methyl-erythromycin 9-[O-[1-(1-Methylethoxy)cyclohexyl]oxime]

Description:

6-O-Methyl-erythromycin 9-[O-[1-(1-Methylethoxy)cyclohexyl]oxime], with the CAS number 156715-14-9, is a semi-synthetic derivative of erythromycin, which is a macrolide antibiotic. This compound exhibits antibacterial properties, primarily targeting Gram-positive bacteria by inhibiting protein synthesis through binding to the 50S ribosomal subunit. The modification at the 6-O position and the introduction of the oxime group enhance its pharmacological profile, potentially improving its efficacy and stability compared to its parent compound. The presence of the cyclohexyl moiety may also influence its lipophilicity and bioavailability. As with other macrolides, it is important to consider its spectrum of activity, resistance patterns, and potential side effects when evaluating its therapeutic use. Additionally, the compound's solubility, stability under various pH conditions, and interaction with other drugs are critical factors in its application in clinical settings. Overall, this compound represents a significant advancement in antibiotic development, aimed at addressing bacterial infections while minimizing resistance.

Formula: C₄₇H₈₆N₂O₁₄

Synonyms:

• Erythromycin, 6-O-methyl-, 9-[O-[1-(1-methylethoxy)cyclohexyl]oxime] (9CI)
• 6-O-Methyl-erythromycin 9-[O-[1-(1-Methylethoxy)cyclohexyl]oxime]
• 6-O-Methylerythromycin A 9-(E)-O-(1-isopropoxycyclohexyl)-oxime

6-O-Methylerythromycin A 9-(E)-O-(1-isopropoxycyclohexyl)-oxime

CAS: 156715-14-9

Formula: C₄₇H₈₆N₂O₁₄

Molecular weight: 903.19

Ref: ST-EA-CP-C1033