CAS 156727-74-1

SNC 80

Description:

SNC 80, with the CAS number 156727-74-1, is a synthetic compound known for its role as a selective agonist for the delta-opioid receptor. It is a member of the class of compounds known as opioid receptor ligands, which interact with the opioid receptors in the brain to produce analgesic effects. SNC 80 is characterized by its high affinity for the delta receptor, which distinguishes it from other opioid compounds that may target mu or kappa receptors. This selectivity is significant in research contexts, particularly in studies exploring pain management and the potential for reduced side effects compared to traditional opioids. The compound has been investigated for its potential therapeutic applications, including its effects on mood and anxiety, as well as its role in modulating pain pathways. However, like many opioid-related substances, its use is subject to regulatory scrutiny due to the potential for abuse and dependence. Overall, SNC 80 serves as an important tool in pharmacological research, contributing to the understanding of opioid receptor dynamics and their implications in medicine.

Formula: C₂₈H₃₉N₃O₂

InChI: InChI=1/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1

InChI key: InChIKey=KQWVAUSXZDRQPZ-UMTXDNHDSA-N

SMILES: [C@H](N1[C@@H](C)CN(CC=C)[C@H](C)C1)(C2=CC(OC)=CC=C2)C3=CC=C(C(N(CC)CC)=O)C=C3

Synonyms:

• (+)-4-[(Ar)-A-((2S,5R)-4-Allyl-2,5-Dimethyl-1-Piperazinyl)-3-Methoxybenzyl]-N,N-Diethylbenzam
• (+)-4-[(Ar)-A-((2S,5R)-4-Allyl-2,5-Dimethyl-1-Piperazinyl)-3-Methoxybenzyl]-N,N-Diethylbenzamide
• (+)-4-[(Ar)-Alpha-((2S,5R)-4-Allyl-2,5-Dimethyl-1-Piperazinyl)-3-Methoxybenzyl]-N,N-Diethylbenzamide
• (+)-4-[(alphaR)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
• 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide
• 4-[(R)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide
• 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(prop-2-en-1-yl)piperazin-1-yl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide
• Benzamide, 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-
• Benzamide, 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-
• Benzamide, 4-[[2,5-dimethyl-4-(2-propenyl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-, [2S-[1(S*),2α,5β]]-
• Nih 10815
• SNC 80

4-[(R)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide

CAS: 156727-74-1

Formula: C₂₈H₃₉N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 449.6282

Ref: IN-DA001OY0

SNC 80

CAS: 156727-74-1

SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.

Formula: C₂₈H₃₉N₃O₂

Purity: 99.65%

Color and Shape: Solid

Molecular weight: 449.63

Ref: TM-T8414

SNC 80

CAS: 156727-74-1

SNC 80

Purity: ≥98%

Molecular weight: 449.63g/mol

Ref: 54-BUP11555

SNC80

CAS: 156727-74-1

Formula: C₂₈H₃₉N₃O₂

Molecular weight: 449.63

Ref: 7W-GK2247

SNC 80

CAS: 156727-74-1

ÎŽ opioid receptor agonist; anti-nociceptive; anti-depressant

Formula: C₂₈H₃₉N₃O₂

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 449.63 g/mol

Ref: 3D-FS27844

SNC 80

Controlled Product

CAS: 156727-74-1

Stability Store in Freezer
Applications SNC 80 is an opioid analgesic and a selective non-peptide μ–δ opioid receptor (1,2,3). It is also an antinociceptive and pro-convulsant agent (1,2).
References (1) Bilsky, E. J., et al.: J. Pharmacol. Exp. Ther., 273, 359 (1995) (2) Calderon, S. N., et al.: J. Med. Chem., 40, 695 (1997) (3) Knapp, R. J., et al.: J. Pharmacol. Exp. Ther., 277, 1284 (1996)

Formula: C₂₈H₃₉N₃O₂

Color and Shape: Neat

Molecular weight: 449.63

Ref: TR-S590000