CAS 15676-19-4

4-amino-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

Description:

4-amino-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, with CAS number 15676-19-4, is a nucleoside analog that exhibits structural features characteristic of both purine and pyrimidine derivatives. This compound contains a pyrrolo[2,3-d]pyrimidine core, which contributes to its potential biological activity, particularly in the context of antiviral and anticancer research. The presence of the 2-deoxy-beta-D-erythro-pentofuranosyl moiety suggests that it can mimic natural nucleosides, potentially interfering with nucleic acid synthesis. The amino group at the 4-position and the carbonitrile group at the 5-position enhance its reactivity and may influence its interaction with biological targets. This compound is of interest in medicinal chemistry due to its potential therapeutic applications, and its unique structure may allow for specific interactions with enzymes or receptors involved in nucleic acid metabolism. Further studies would be necessary to elucidate its pharmacological properties and mechanisms of action.

Formula: C₁₂H₁₃N₅O₃

InChI: InChI=1/C12H13N5O3/c13-2-6-3-17(9-1-7(19)8(4-18)20-9)12-10(6)11(14)15-5-16-12/h3,5,7-9,18-19H,1,4H2,(H2,14,15,16)/t7-,8+,9+/m0/s1

7-Cyano-7-deaza-2'-deoxyadenosine

CAS: 15676-19-4

7-Cyano-7-deaza-2'-deoxyadenosine is a nucleoside analog that inhibits the growth of virus by competing with deoxyadenosine for incorporation into DNA and RNA. 7-Cyano-7-deaza-2'-deoxyadenosine also stabilizes dna duplexes and prevents them from breaking down. It has been shown to be effective against herpes simplex virus, which causes painful blisters on the skin or genitals. This drug has been used in clinical trials as an antiviral agent. 7-Cyano-7-deaza-2'-deoxyadenosine is synthesized from 2',3'-didehydrocytidine under the following conditions:

Formula: C₁₂H₁₃N₅O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 275.26 g/mol

Ref: 3D-NC144684