CAS 156774-35-5

Methyl (1S,2S,3S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

Description:

Methyl (1S,2S,3S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, with CAS number 156774-35-5, is a synthetic organic compound characterized by its complex bicyclic structure, which includes a nitrogen atom in the bicyclic framework. This compound features multiple functional groups, including a carboxylate ester and a methoxy group, contributing to its chemical reactivity and potential biological activity. The presence of fluorinated phenyl groups enhances its lipophilicity, which may influence its pharmacokinetic properties. The stereochemistry indicated by the (1S,2S,3S,5R) configuration suggests specific spatial arrangements that can significantly affect the compound's interactions with biological targets, potentially making it relevant in medicinal chemistry. Its structural complexity and functionalization suggest potential applications in drug development, particularly in areas targeting neurological or psychiatric conditions, although specific biological activities would require empirical investigation. Overall, this compound exemplifies the intricate design often found in pharmaceutical chemistry, where modifications can lead to significant changes in activity and selectivity.

Formula: C₂₃H₂₅F₂NO₃

InChI: InChI=1S/C23H25F2NO3/c1-26-18-11-12-19(26)21(23(27)28-2)20(13-18)29-22(14-3-7-16(24)8-4-14)15-5-9-17(25)10-6-15/h3-10,18-22H,11-13H2,1-2H3/t18-,19+,20+,21+/m1/s1

InChI key: InChIKey=XSYGBVSQKPLETJ-ANULTFPQSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(N(C)[C@@](C[C@@H]1OC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)(CC2)[H])[H]

Synonyms:

• 2-Carbomethoxy-3-(bis(4-fluorophenyl)methoxy)tropane
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-[bis(4-fluorophenyl)methoxy]-8-methyl-, methyl ester, (1S,2S,3S,5R)-
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-[bis(4-fluorophenyl)methoxy]-8-methyl-, methyl ester, [1S-(2-exo,3-endo)]-
• O 620
• methyl (1S,2S,3S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
• Difluoropine

8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-[bis(4-fluorophenyl)methoxy]-8-methyl-, methyl ester, (1S,2S,3S,5R)-

CAS: 156774-35-5

Formula: C₂₃H₂₅F₂NO₃

Molecular weight: 401.4463

Ref: IN-DA001OZ5

Methyl (1S,2S,3S,5R)-3-[Bis(4-Fluorophenyl)Methoxy]-8-Methyl-8-Azabicyclo[3.2.1]Octane-2-Carboxylate

Controlled Product

CAS: 156774-35-5

Methyl (1S,2S,3S,5R)-3-[Bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate is a molecule that has been shown to bind with high affinity to the serotonin receptor and blocks dopamine uptake. This drug has also demonstrated dose-dependent locomotor activity in rats and m1 muscarinic receptor binding. Methyl (1S,2S,3S,5R)-3-[Bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate is being developed for use as a diagnostic tool for detecting Parkinsonian symptoms or chemical reactions in the brain.

Formula: C₂₃H₂₅F₂NO₃

Purity: Min. 95%

Molecular weight: 401.45 g/mol

Ref: 3D-FM102464