CAS 15690-57-0

Enclomiphene

Description:

Enclomiphene is a selective estrogen receptor modulator (SERM) primarily used in the treatment of male hypogonadism and infertility. It is a stereoisomer of clomiphene, which is commonly used in fertility treatments for women. Enclomiphene functions by blocking estrogen receptors in the hypothalamus, leading to an increase in the secretion of gonadotropins, which in turn stimulates the production of testosterone and sperm in men. This compound is characterized by its ability to selectively modulate estrogen activity, promoting endogenous testosterone production while minimizing the side effects associated with traditional testosterone replacement therapies. Enclomiphene is typically administered orally and has a favorable pharmacokinetic profile, allowing for effective absorption and distribution in the body. Its therapeutic applications extend beyond fertility, as it may also have potential benefits in conditions related to low testosterone levels. However, as with any medication, it is essential to consider potential side effects and contraindications, and its use should be guided by a healthcare professional.

Formula: C₂₆H₂₈ClNO

InChI: InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25+

InChI key: InChIKey=GKIRPKYJQBWNGO-OCEACIFDSA-N

SMILES: C(=C(/Cl)\C1=CC=CC=C1)(\C2=CC=C(OCCN(CC)CC)C=C2)/C3=CC=CC=C3

Synonyms:

• (E)-Clomiphene
• 2-[4-[(1E)-2-Chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine
• 2-[p-(2-Chloro-trans-1,2-diphenylvinyl)phenoxy]triethylamine
• 2-{4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy}-N,N-diethylethanamine
• Androxal
• Cisclomifene
• Enclomiphene
• Ethanamine, 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethyl-, (E)-
• Ethanamine, 2-[4-[(1E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethyl-
• Ici 46476
• Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, (E)-
• trans-Clomifene

Ethanamine, 2-[4-[(1E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethyl-

CAS: 15690-57-0

Formula: C₂₆H₂₈ClNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 405.9596

Ref: IN-DA001P2E

trans-Clomiphene (Enclomiphene)

CAS: 15690-57-0

Formula: C₂₆H₂₈ClNO

Color and Shape: White To Off-White Solid

Molecular weight: 405.97

Ref: 4Z-C-822

trans-Clomiphene

Controlled Product

CAS: 15690-57-0

Clomiphene is a drug that is used to treat female infertility. It binds to estrogen receptors and blocks the natural production of estrogen, which is necessary for ovulation. Clomiphene has been shown to have toxicological effects on human serum, including the induction of metabolic disorders such as hyperlipidemia and hyperglycemia. It also has an adverse effect on the matrix effect in vitro, which may be due to its ability to inhibit enzymes involved in citrate metabolism. Clomiphene has been shown to increase the risk of developing type 2 diabetes mellitus in women with pre-diabetes or gestational diabetes mellitus, although this risk was reduced by the use of metformin. Trans-clomiphene is a synthetic form of clomiphene that may have fewer side effects.

Formula: C₂₆H₂₈ClNO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 406 g/mol

Ref: 3D-QAA69057

Trans-Clomiphene

CAS: 15690-57-0

Formula: C₂₆H₂₈ClNO

Molecular weight: 406

Ref: ST-EA-CP-C29028