CAS 157026-18-1

2-Amino-5-Bromo-3-Nitrobenzotrifluoride

Description:

2-Amino-5-Bromo-3-Nitrobenzotrifluoride, with the CAS number 157026-18-1, is an organic compound characterized by the presence of an amino group, a bromine atom, and a nitro group attached to a benzene ring that also contains three trifluoromethyl groups. This compound is typically a solid at room temperature and exhibits a complex structure due to the presence of multiple functional groups, which can influence its reactivity and solubility. The amino group (-NH2) can participate in hydrogen bonding, while the nitro group (-NO2) is known for its electron-withdrawing properties, affecting the compound's overall electronic characteristics. The trifluoromethyl groups (-CF3) contribute to the compound's lipophilicity and can enhance its stability and resistance to degradation. Due to these features, 2-Amino-5-Bromo-3-Nitrobenzotrifluoride may find applications in various fields, including pharmaceuticals and agrochemicals, where its unique properties can be utilized for specific chemical reactions or as intermediates in synthesis.

Formula: C₇H₄BrF₃N₂O₂

InChI: InChI=1/C7H4BrF3N2O2/c8-3-1-4(7(9,10)11)6(12)5(2-3)13(14)15/h1-2H,12H2

SMILES: c1c(cc(c(c1C(F)(F)F)N)N(=O)=O)Br

Synonyms:

• 4-Brom-2-nitro-6-(trifluormethyl)anilin
• 4-Bromo-2-nitro-6-(trifluoromethyl)aniline
• Benzenamine, 4-bromo-2-nitro-6-(trifluoromethyl)-

Benzenamine, 4-bromo-2-nitro-6-(trifluoromethyl)-

CAS: 157026-18-1

Formula: C₇H₄BrF₃N₂O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 285.0181

Ref: IN-DA001P6A

2-Amino-5-bromo-3-nitrobenzotrifluoride

CAS: 157026-18-1

2-Amino-5-bromo-3-nitrobenzotrifluoride

Purity: 98%

Color and Shape: Solid

Molecular weight: 285.02g/mol

Ref: 54-PC48440

2-Amino-5-bromo-3-nitrobenzotrifluoride

CAS: 157026-18-1

Formula: C₇H₄BrF₃N₂O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 285.02

Ref: 10-F036302

4-Bromo-2-nitro-6-(trifluoromethyl)aniline

Controlled Product

CAS: 157026-18-1

Applications 4-Bromo-2-nitro-6-(trifluoromethyl)aniline is a reagent for the preparation of 3-(5-arylbenzimidazol-2-yl)-1-oxa-2-azaspiro[4.5]decenes, a transient receptor potential melastatin 8 (TRPM8) antagonist for the treatment of painful conditions related to cold.
References Parks, D. J., et al.: J. Med. Chem., 54, 233-247 (2011);

Formula: C₇H₄BrF₃N₂O₂

Color and Shape: Neat

Molecular weight: 285.02

Ref: TR-B699340