CAS 157199-28-5

Desmethyl Cerivastatin, Sodium Salt

Description:

Desmethyl Cerivastatin, Sodium Salt is a chemical compound that is a derivative of cerivastatin, a statin used to lower cholesterol levels. It is characterized by the absence of a methyl group at the 4-position of the cerivastatin structure, which influences its pharmacological properties. As a sodium salt, it is typically more soluble in water compared to its parent compound, enhancing its bioavailability. The compound functions primarily as an inhibitor of HMG-CoA reductase, an enzyme crucial in the cholesterol biosynthesis pathway, thereby effectively reducing low-density lipoprotein (LDL) cholesterol levels in the bloodstream. Its structural modifications may also affect its potency and side effect profile compared to other statins. In terms of safety, like other statins, it may carry risks of muscle-related side effects and liver enzyme alterations, necessitating monitoring during use. Overall, Desmethyl Cerivastatin, Sodium Salt represents a significant compound in the realm of lipid-lowering therapies, contributing to cardiovascular health management.

Formula: C₂₅H₃₁FNNaO₅

InChI: InChI=1/C25H32FNO5.Na/c1-14(2)24-20(10-9-18(29)11-19(30)12-22(31)32)23(16-5-7-17(26)8-6-16)21(13-28)25(27-24)15(3)4;/h5-10,14-15,18-19,28-30H,11-13H2,1-4H3,(H,31,32);/q;+1/p-1/b10-9+;/t18-,19-;/m1./s1

SMILES: CC(C)c1c(C=CC(CC(CC(=O)O)O)O)c(c2ccc(cc2)F)c(CO)c(C(C)C)n1.[Na]

Synonyms:

• [R*,S*-(E)]-7-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6-heptenoic Acid Monosodium Salt
• M-1 Metabolit
• M-1 Metabolite

Desmethyl Cerivastatin, Sodium Salt

Controlled Product

CAS: 157199-28-5

Formula: C₂₅H₃₁FNO₅·Na

Color and Shape: Neat

Molecular weight: 467.51

Ref: TR-D291530