CAS 15722-48-2

Olsalazine

Description:

Olsalazine is a chemical compound primarily used as a medication for the treatment of ulcerative colitis, a form of inflammatory bowel disease. It is a prodrug that is converted in the colon to mesalamine, which exerts anti-inflammatory effects. Olsalazine is characterized by its chemical structure, which includes a diazo bond linking two mesalamine molecules. This structure allows for targeted delivery of the active ingredient to the colon, minimizing systemic absorption and potential side effects. The compound is typically administered orally and is known for its relatively good tolerability profile. In terms of solubility, olsalazine is sparingly soluble in water, which is a consideration in its formulation. Its pharmacokinetics involve metabolism primarily in the gastrointestinal tract, with the therapeutic effects being attributed to the release of mesalamine. Overall, olsalazine represents an important therapeutic option for managing chronic inflammatory conditions of the gastrointestinal tract.

Formula: C₁₄H₁₀N₂O₆

InChI: InChI=1S/C14H10N2O6/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22/h1-6,17-18H,(H,19,20)(H,21,22)

InChI key: InChIKey=QQBDLJCYGRGAKP-UHFFFAOYSA-N

SMILES: N(=NC1=CC(C(O)=O)=C(O)C=C1)C2=CC(C(O)=O)=C(O)C=C2

Synonyms:

• 3,3'-Azobis(6-hydroxybenzoic acid)
• 3,3'-Dicarboxy-4,4'-dihydroxyazobenzene
• 3,3′-(1,2-Diazenediyl)bis[6-hydroxybenzoic acid]
• 5,5'-Azobis(salicylic acid)
• 5,5'-Azodisalicylic acid
• Azodisal
• Benzoic acid, 3,3'-(1,2-diazenediyl)bis[6-hydroxy-
• Olsalazine
• Salicylic acid, 5,5'-azodi-
• 3,3'-(E)-diazene-1,2-diylbis(6-hydroxybenzoic acid)
• Olsalazine [INN:BAN]
• Benzoic acid, 3,3′-azobis[6-hydroxy-
• C.I. Mordant Yellow 5

Olsalazine

CAS: 15722-48-2

Formula: C₁₄H₁₀N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 302.2390

Ref: IN-DA01EGCF

Olsalazine

CAS: 15722-48-2

Olsalazine

Purity: ≥98%

Molecular weight: 302.24g/mol

Ref: 54-BUP06870

Olsalazine-13C6

CAS: 15722-48-2

Formula: C₈₁₃C₆H₁₀N₂O₆

Color and Shape: Yellow Solid

Molecular weight: 308.20

Ref: 4Z-O-2212

Olsalazine Sodium

CAS: 15722-48-2, 6054-98-4

Formula: C₁₄H₈N₂Na₂O₆

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 346.21

Ref: 3B-O0517

Olsalazine

CAS: 15722-48-2

Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.

Formula: C₁₄H₁₀N₂O₆

Purity: 99.31%

Color and Shape: Solid

Molecular weight: 302.24

Ref: TM-T20615

Olsalazine

CAS: 15722-48-2

Purity: 95%

Molecular weight: 302.2420044

Ref: 10-F600610