
CAS 157327-97-4
:Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxy-N-(2-methyl-1-oxopropyl)-, 2′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
Description:
Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxy-N-(2-methyl-1-oxopropyl)-, 2′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a guanosine base, which is one of the four nucleobases in RNA, linked to a phosphoramidite moiety that facilitates its incorporation into DNA or RNA strands during synthesis. The presence of methoxyphenyl groups enhances its stability and solubility, while the cyanoethyl group contributes to its reactivity in phosphoramidite chemistry. The compound is characterized by its ability to form stable bonds with complementary nucleotides, making it valuable for applications in molecular biology, such as gene synthesis, antisense oligonucleotide development, and RNA interference studies. Its specific structure allows for precise modifications, which can be tailored for various experimental needs, highlighting its importance in research and therapeutic contexts.
Formula:C44H54N7O8P
InChI:InChI=1S/C44H54N7O8P/c1-28(2)40(52)48-43-47-39-38(41(53)49-43)46-27-50(39)42-37(59-60(57-24-12-23-45)51(29(3)4)30(5)6)25-36(58-42)26-56-44(31-13-10-9-11-14-31,32-15-19-34(54-7)20-16-32)33-17-21-35(55-8)22-18-33/h9-11,13-22,27-30,36-37,42H,12,24-26H2,1-8H3,(H2,47,48,49,52,53)/t36-,37+,42+,60?/m0/s1
InChI key:InChIKey=XYRJDHYBLIRQDU-SRBSNSDWSA-N
SMILES:C(OC[C@H]1O[C@H]([C@H](OP(N(C(C)C)C(C)C)OCCC#N)C1)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Synonyms:- Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxy-N-(2-methyl-1-oxopropyl)-, 2′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
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Found 1 products.
2'-dG (iBu)-2'-phosphoramidite
CAS:<p>2'-dG (iBu)-2'-phosphoramidite is a Nucleoside Phosphoramidite.</p>Formula:C44H54N7O8PColor and Shape:SolidMolecular weight:839.92
