CAS 157355-79-8

Fmoc-D-His-OH

Description:

Fmoc-D-His-OH, or 9-fluorenylmethoxycarbonyl-D-histidine, is a protected form of the amino acid D-histidine, commonly used in peptide synthesis. The Fmoc group serves as a protective moiety that allows for selective deprotection during the synthesis process. This compound is characterized by its ability to form stable peptide bonds, making it valuable in the construction of peptides and proteins. Fmoc-D-His-OH is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but less soluble in water. Its structure includes a histidine side chain, which can participate in various biochemical interactions due to its imidazole group, contributing to the overall properties of the peptides it forms. The compound is widely utilized in research and pharmaceutical applications, particularly in the development of biologically active peptides. Proper handling and storage are essential, as with many chemical substances, to maintain its stability and efficacy.

Formula: C₂₁H₁₉N₃O₄

Synonyms:

• N-Alpha-(9-Fluorenylmethoxycarbonyl)-D-Histidine
• Fmoc-D-Histidine

D-Histidine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 157355-79-8

Formula: C₂₁H₁₉N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 377.3933

Ref: IN-DA001PE4

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-histidine

CAS: 157355-79-8

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-histidine

Purity: 95%

Molecular weight: 377.39g/mol

Ref: 54-OR1001882

Fmoc-D-His

CAS: 157355-79-8

Formula: C₂₁H₁₉N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 377.4

Ref: 10-F222160

Nα-Fmoc-D-histidine

Controlled Product

CAS: 157355-79-8

Applications Nα-Fmoc-D-histidine is an N-Fmoc-protected form of D-Histidine (H456015). D-Histidine is the unnatural, biologically inactive isomer of L-Histidine (H456010). D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine.
References Aiken, S., et al.: J. Phys., 445, 69 (1992); Caldara, M., et al.: J. Mol. Bio., 373, 251 (2007); Grula, E. & Grula, M.: Biochim. Biophys. Acta, 74, 776 (1963)

Formula: C₂₁H₁₉N₃O₄

Color and Shape: Neat

Molecular weight: 377.39

Ref: TR-F633005