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CAS 157355-81-2

:

Fmoc-D-Thr-OH

Description:
Fmoc-D-Thr-OH, or 9-fluorenylmethoxycarbonyl-D-threonine, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The D-threonine component indicates that the amino acid is in its D-enantiomer form, which is less common than the L-form in biological systems. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, but less soluble in water. The Fmoc group can be removed under basic conditions, facilitating the subsequent coupling of amino acids in peptide synthesis. Fmoc-D-Thr-OH is utilized in various applications, including the development of pharmaceuticals and in the study of protein structure and function. Its stability and ease of handling make it a valuable reagent in organic and medicinal chemistry.
Formula:C19H19NO5
InChI:InChI=1/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11?,17-/m1/s1
SMILES:CC([C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O
Synonyms:
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-D-Threonine
  • N-Alpha-Fmoc-D-Threonine
  • N-Alpha-Fmoc-D-Threonine / (2R,3S)
  • Fmoc-D-Thr
  • Fmoc-D-Threonine
  • Fmoc-D-Thr Br
  • N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-threonine
  • N-Fmoc-D-Threonine
  • FMOC-D-THREONINE extrapure
  • N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-allothreonine
  • See more synonyms
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