CAS 157401-01-9

(3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester

Description:

The chemical substance known as (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester, with the CAS number 157401-01-9, is a derivative of cholesterol characterized by the presence of three hydroxyl groups at specific positions on the steroid nucleus. This compound features a unique structure that includes a double bond in the steroid backbone, contributing to its biological activity. The ethyl ester functional group enhances its lipophilicity, which may influence its absorption and distribution in biological systems. This compound is of interest in various fields, including biochemistry and pharmacology, due to its potential roles in cellular signaling and membrane dynamics. Its hydroxyl groups can participate in hydrogen bonding, affecting its solubility and interaction with other biomolecules. Overall, this substance exemplifies the complexity of steroid derivatives and their potential applications in medicinal chemistry and therapeutic development.

Formula: C₂₉H₄₈O₅

Synonyms:

• Cholest-24-en-26-oic acid, 3,7,12-trihydroxy-, ethyl ester, (3α,5β,7α,12α)- (9CI)
• )-3,7,12-Trihydroxy-cholest-24-en-26-oicAcidEthylEster
• (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester

(3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester

Controlled Product

CAS: 157401-01-9

Applications (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester is an intermediate in the synthesis of (25R)-3β,7α,12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood.
References Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000); Bjorkhem, I.: J. Clin. Invest., 6, 725(2002); Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)

Formula: C₂₉H₄₈O₅

Color and Shape: Neat

Molecular weight: 476.35

Ref: TR-T887910