CAS 1576-45-0

3-(Phenylsulfamoyl)benzoic acid

Description:

3-(Phenylsulfamoyl)benzoic acid, with the CAS number 1576-45-0, is an organic compound characterized by the presence of a benzoic acid moiety substituted with a phenylsulfamoyl group. This compound features a sulfonamide functional group, which is known for its ability to form hydrogen bonds and participate in various chemical reactions. The presence of the phenyl group enhances its lipophilicity, potentially influencing its biological activity and solubility properties. Typically, compounds like this exhibit moderate to high melting points and may be soluble in polar organic solvents. The sulfonamide group can impart antibacterial properties, making such compounds of interest in medicinal chemistry. Additionally, the structural arrangement allows for potential interactions with biological targets, which can be explored for therapeutic applications. Overall, 3-(Phenylsulfamoyl)benzoic acid is a compound of interest in both synthetic and medicinal chemistry due to its unique functional groups and potential biological activities.

Formula: C₁₃H₁₁NO₄S

InChI: InChI=1S/C13H11NO4S/c15-13(16)10-5-4-8-12(9-10)19(17,18)14-11-6-2-1-3-7-11/h1-9,14H,(H,15,16)

InChI key: InChIKey=YNRKZIPFWSDERE-UHFFFAOYSA-N

SMILES: S(NC1=CC=CC=C1)(=O)(=O)C2=CC(C(O)=O)=CC=C2

Synonyms:

• 3-[(Phenylamino)sulfonyl]benzoic acid
• Benzoic acid, 3-[(phenylamino)sulfonyl]-
• 3-(Phenylsulfamoyl)benzoic acid
• Benzoic acid, m-(phenylsulfamoyl)-
• 3-[(Phenylamino)sulfonyl]benzenecarboxylic acid

Belinostat Impurity 2

CAS: 1576-45-0

Formula: C₁₃H₁₁NO₄S

Molecular weight: 277.29

Ref: 4Z-B-130011

3-(Anilinosulfonyl)-benzenecarboxylic Acid -D5

Controlled Product

CAS: 1576-45-0

Applications 3-(Anilinosulfonyl)-benzenecarboxylic Acid -D5 is the labeled compound of 3-(Anilinosulfonyl)-benzenecarboxylic Acid (3-ASBA) (A157600). 3-(Anilinosulfonyl)-benzenecarboxylic Acid (3-ASBA) is used in preparation of N-hydroxy[(phenylsulfamoyl)phenyl]acrylamides useful as histone deacetylase inhibitors for the treatment of cancer.
References Yihan, W., et al.: Patents, (2017),

Formula: C₁₃D₅H₆NO₄S

Color and Shape: Neat

Molecular weight: 282.327

Ref: TR-A157602

3-(Anilinosulfonyl)-benzenecarboxylic Acid (3-ASBA)

Controlled Product

CAS: 1576-45-0

Formula: C₁₃H₁₁NO₄S

Color and Shape: Neat

Molecular weight: 277.296

Ref: TR-A157600